statistical considerations for use of composite health-related quality-of-life scores in randomized trials

Answers

Answer 1

Statistical considerations for the use of composite health-related quality-of-life scores in randomised trials

This is a research paper whose author is Andrew J. Vickers.

Abstract:

background: In randomised studies, first-rate of life measures are mechanically utilised as outcomes. contraptions with several subscales provide researchers the choice of combining a few or all scales right into a unmarried composite score. There is probably diverse clinically and scientifically sound alternative subscale combinations for the predominant outcome degree.foremost findings: The statistical effectiveness of diverse subscale combinations is decided with the aid of the relative effect size of the intervention on every subscale as well as the correlation between the subscales. easy formulae may be installed to determine the relative statistical efficiency of each clinically appropriate subscale aggregate. Hypothetical situations imply that the variety of participants required in a scientific trial is probably twice as huge for a few subscale combinations as for others.

Conclusions:

Ina randomised examine, there are often robust scientific or scientific reasons to pick a positive subscale or composite.whilst there are several viable picks, statistical performance can help in guiding the choice of endpoint.

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Related Questions

the ceo of a large company decides to survey the workers for their opinions about a new vacation policy. a sample of the population that gives each worker an equal chance of participating in the survey would be a(n): please choose the correct answer from the following choices, and then select the submit answer button. answer choices sample that includes half the workers. random sample. unrepresentative sample. sample that includes all the workers.

Answers

correct answer is random sample

A simple random sample, also known as an SRS, is a subset of people (also known as a sample) picked at random from a larger group of people (also known as a population) with an equal probability. It is a method of choosing a sample at random. Each subset of k people in SRS has the same chance of getting selected for the sample as any other subset of k people. [1] An objective sampling strategy is a straightforward random sample. Simple random sampling is a fundamental kind of sampling that may be used in combination with other, more sophisticated sampling techniques.

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there are 20 colored markers in a package – 8 black, 4 blue, 4 red, 4 green. if two markers are selected at random, one after another, without replacement, find the probability that both will be blue.

Answers

If two markers are selected at random, one after another, without replacement, the probability that both will be blue = 0.0316

For given question,

there are 20 colored markers in a package – 8 black, 4 blue, 4 red, 4 green.

if two markers are selected at random, one after another, without replacement, we need to find the probability that both will be blue.

The probability that the selecting one blue marker is:

4/20

After selecting one blue marker, there are 19 markers in a package -  8 black, 3 blue, 4 red, 4 green.

The probability of selecting second blue marker would be,

3/19

So, the probability that both will be blue:

4/20 × 3/19

= 0.2 × 0.16

= 0.0316

Therefore, if two markers are selected at random, one after another, without replacement, the probability that both will be blue = 0.0316

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976,733,776 divide 9

Answers

Answer:

108525975,11111111111111111111111

Answer: 108525975.111

Step-by-step explanation:

Darren is purchasing a car that costs $11,000. He is taking out a simple interest loan at an annual rate of 3%. If he makes monthly payments over a period of 5 years, how much is his monthly payment?

Answers

Darren's monthly payment on car loan is $210.83

Given,

Cost of the car Darren purchased = $11000

The simple interest for the car loan = 3%

Time period of loan = 5 years

We have to find the monthly payment amount:

Simple interest = PRT / 100

Where,

P = Principal amount = $11000

R = Rate of interest = 3%

T = Time period = 5 years

Now,

SI = PRT / 100

SI = (11000 × 3 × 5) / 100

SI = 110 × 3 × 5

SI = 1650

Here, the simple interest for 5 years is $1650

Now,

Total amount to be paid after 5 years = Principal amount + Simple interest

A = P + SI

A = 11000 + 1650

A = 12650

The amount to be paid after 5 years is $12650

Next,

The monthly payment amount:

Number of months in 5 years = 12 × 5 = 60 months

So,

Monthly payment amount = Total amount after 5 years / Total months in 5 years

Monthly payment amount = 12650 / 60 = 210.83

That is, the monthly payment amount on car loan is $210.83

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Tomás wants to tile a rectangular floor with square tiles that measure 12 inches on a side. The floor measures 10 feet 6 inches long by 8 feet 6 inches wide. If he is able to cut the tiles without waste, what is the minimum whole number of tiles Tomás needs to completely cover the floor?​

Answers

There are 1176 is the minimum whole number of tiles Tomás needs to completely cover the rectangular floor.

Rectangle:

Rectangle means a four sided-polygon, having all the internal angles equal to 90 degrees. The two sides at each corner or vertex, meet at right angles.

Given,

Tomás wants to tile a rectangular floor with square tiles that measure 12 inches on a side. The floor measures 10 feet 6 inches long by 8 feet 6 inches wide.

Here we need to find if he is able to cut the tiles without waste, what is the minimum whole number of tiles Tomás needs to completely cover the floor.

Here we have to convert the feet into inches for easy calculation,

1 feet = 12 inches

So, the length is ,

l = 120 + 6 = 126 inches

w = 96 + 6 = 112 inches

So, the area of the floor is,

=> l x w

=> 126 x 112

=> 14,112

Here we need to use 12inches square tile,

So,

=> 14112 / 12

=> 1176.

Therefore, there are 1176 tiles are need to cover the floor.

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Which of the following is the equation of a line in slope-intercept form for a
line with slope = 2/3 and y-intercept at (0,-2)

Answers

The equation of the line with slope 2/3 and y-intercept at ( 0, - 2) is y = ( 2/3 )x - 2.

The slope-intercept form is the way to write a line's equation so that the y-intercept (where the line crosses the vertical y-axis) and slope (steepness) are instantly visible.

We have the slope 2/3 of a line and the y-intercept at ( 0, - 2 ).

Now, we know that

The slope-intercept form of the equation of a line with slope m and y-intercept at the point (0, c) is given by:

y = mx + c

The slope of the line is :

m = 2/3

And, the y-intercept is (0, c) = ( 0, -2)

Hence, the equation of the line in the slope-intercept form will be:

y = mx + c

y = ( 2/3 )x + ( - 2)

y = ( 2/3 )x - 2

Therefore, the slope-intercept form of the equation of the line is y = ( 2/3 )x - 2.

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(ANSWER QUICK PLEASE) 1. Kasey noticed that the distribution of candy bars in the variety bags of candy bars is always the same. There are three times as many Twix Bars as Milky Ways. There are 5 fewer snickers than there are Twix.

Answers

Small Twix : 24 ( 8*3)
Small Snickers :19 (24-5)

Medium Milky Way : 10 (30/3)
Medium snickers : 25. (30-5)

Large Twix: 42 (37+5)
Large Milky Way 14 (42/3)


Hope this helps!

Answer:

Let's call the number of Twix bars "x".

Since there are three times as many Twix bars as Milky Ways, the number of Milky Ways is x / 3.

And, since there are 5 fewer Snickers bars than there are Twix bars, the number of Snickers bars is x - 5.

So, the total number of candy bars can be found by adding the number of each type of candy bar:

x + x / 3 + x - 5 = total number of candy bars

Combining like terms, we get:

5x / 3 - 5 = total number of candy bars

To find the value of x, we can solve this equation for x.

5x / 3 = total number of candy bars + 5

5x / 3 = total number of candy bars + 5

5x = 3(total number of candy bars + 5)

5x = 3(total number of candy bars) + 15

5x = 3(total number of candy bars) + 15

5x - 15 = 3(total number of candy bars)

5x - 15 = 3(total number of candy bars)

(5x - 15) / 3 = total number of candy bars

So, the total number of candy bars can be found by dividing (5x - 15) by 3. The value of x represents the number of Twix bars, and the rest of the candy bars can be found using the relationships described in the problem.

a double decker bridge has two parallel levels connected by a network of diagonal girders. one of the girders makes 52 degrees angle with the lower level as shown in the figure. what is the measure of angle 1?

Answers

Answer: 128

Step-by-step explanation:

a whole supplementary angle adds up to 180 degrees

so 180

   - 52

               

     128

a box with a square base and a top is to be constructed from 10 square meters of material. find the dimensions which will maximize the volume that the box can hold.

Answers

A box with a square base and a top is to be constructed from 10 square meters of material. 40 square meters will maximize the volume that the box can hold.

What is volume?

LSD use among secondary school understudies is a specific concern. More Volume is a proportion of consumed three-layered space. It is frequently evaluated mathematically utilizing SI inferred units or by different supreme units. Volume is characterized as the space involved inside the limits of an article in three-layered space. It is otherwise called the limit of article. Volume is a proportion of consumed three-layered space. It is frequently measured mathematically utilizing the SI determined unit, the cubic meter. The volume of a compartment is by and large comprehended to be the limit of the compartment, how much liquid (gas or fluid) that the holder could hold, instead of how much space the actual holder dislodges. Three layered numerical shapes are additionally relegated volumes.

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PLS HELP!!

what are the two equations to set up to solve the equation

| 3x -2 | = 19
3x - 2 =
insert in the box and 3x - 2 = insert in the box

Answers

The two equations to set up to solve the equation are 3x - 2 = 19 and 3x - 2 = -19

What are the two equations to set up to solve the equation?

The equation is given as

|3x - 2| = 19

The above equation is an absolute value equation.

When it is split, the constant would be represented as positive and negative

So, the equivalent equations are

3x - 2 = 19 and 3x - 2 = -19

Hence, the two equations to set up to solve the equation are 3x - 2 = 19 and 3x - 2 = -19

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The diameter of a circle is 36 meters. What is the circle's area? Use 3.14

Answers

Answer:

113.04

Step-by-step explanation:

Stephen bought some peaches and crumbles to make peach cobbler. Peaches costs $1.80 per pound, and crumbles cost $2.50 per pound. Stephen spent a total of $19.40.
Part 1. Create an equation that can be used to determine the number of pounds of peaches and crumbles that Stephen could have purchased. Remember to define any variables used.
Part 2. Use the equation created in Part 1 to determine how many pounds of crumbles Stephen purchased if he purchased 8 pounds of peaches. You must show all steps to receive credit.
√x

Answers

The equation which can be used to determine the number of pounds of peaches and crumbles that Stephen could have purchased is 1.8x+2.5y=19.4 and if Stephen purchased 8 pounds of peaches then he also purchased 2 pounds of crumbles.

Given that the cost of peaches is $1.80 per pound and cost of crumbles is $2.50 per pound and the total expenditure done by Stephen is $19.40.

We are required to find the equation that can be used to determine the number of pounds of peaches and crumbles that Stephen could have purchased and find the number of crumbles that Stephen purchased if he had 8 pounds of peaches.

Suppose the number of pounds of peaches be x and the number of crumbles be y.

The equation will be as under:

x*1.80+y*2.50=19.40

1.80x+2.50y=19.40---------1

Put the value of x=8 to find the number of crumbles.

1.8 *8+2.50y=19.40

14.4+2.50y=19.40

2.50y=19.4-14.4

2.50y=5

y=5/2.5

y=50/25

y=2

Hence the equation which can be used to determine the number of pounds of peaches and crumbles that Stephen could have purchased is 1.8x+2.5y=19.4 and if Stephen purchased 8 pounds of peaches then he also purchased 2 pounds of crumbles.

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The function m(x) represents the amount of money (in dollars) it costs you to be a member at the YMCA after x monthsExplain the meaning of the following function notation using a sentence by connecting it to this situation:

m(0) = 50

Answers

The meaning of the function notation is the inital amount of money (in dollars) it costs you to be a member at the YMCA

How to explain the meaning of the function notation?

The function is given as

m(x) represents the amount of money (in dollars) it costs you to be a member at the YMCA after x months

The function notation is given as

m(0)

The function notation m(0) implies that

We determine the value of m(x) when x = 0

This represents the x-intercept of the function

The x-intercept of the function is the initial value of the function

Hence, the meaning of the function notation is the inital amount of money (in dollars) it costs you to be a member at the YMCA

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A​ town's population is . 57,900 About 75 people move out of the town each month. Each​ month, 200 people on average move into town. A nearby town has a population of 60,600 . It has no one moving in and an average of 175 people moving away every month. In about how many months will the populations of the towns be​ equal? Write an equation to model the situation. Then solve the equation and answer the question.

Answers

The populations of both towns would be​ equal in nine months.

What is the equation?

The equation is defined as mathematical statements that have a minimum of two terms containing variables or numbers that are equal.

Let's assume that both town's populations will be equal in x months.

After x months, the population of the first town is given by

200x - 75x + 57,900  

The population of the second town after x months is  given by

60,600 - 175x

In order for the population of both towns to be equal, we have

200x - 75x + 57,900 = 60,600 - 175x

This is the required equation that represents the given situation.

200x - 75x + 57,900 = 60,600 - 175x

Rearrange the likewise terms and apply arithmetic operation

200x - 75x + 175x = 60,600 - 57,900

300x = 2700

x = 2700/300

x = 9

Therefore, the populations of both towns would be​ equal in nine months.

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Write and equations of the horizontal and vertical lines that pass though the given point.
(-3,2)
(1,4)

Answers

Answer:

Step-by-step explanation:

(-3, 2)

Horizontal is y = 2

Vertical is x = -3

In the same way (1, 4) is

y = 4

x = 1.

x^2=a^2, what does x equal?

Answers

x=±a

1. take the square root of both sides

PLS HELP ASAP!!

Three less than the quotient of a number and two has a result of thirteen. What would the solution be? Please only place the number.

Thanks a ton!!!

Answers

The solution of the of the expression is as follows:

x = 32

How to find solution to expression?

Three less than the quotient of a number and two has a result of thirteen.

Therefore,

let

the number = x

The quotient of the number and two  = x / 2

Therefore,

x  / 2 - 3 = 13

add 3 to both sides

x  / 2 - 3 = 13

x  / 2 - 3 + 3 = 13 + 3

x / 2 = 16

cross multiply

x = 2 × 16

x = 32

Therefore, the solution of the of the expression is as follows:

x = 32

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Help please! (show steps too)

Answers

If the equation of the circle is [tex]x^{2} +y^{2}-8x+6=0[/tex] then the center and radius of the circle is (4,0) and [tex]\sqrt{10}[/tex] respectively

Given,

The equation,

[tex]x^{2} +y^{2}-8x+6=0[/tex]

Rearrange the equation

[tex]x^{2} -8x+6+y^{2} =0[/tex]

Add 10 on both sides

[tex]x^{2} -8x+16+y^{2} =10[/tex]

Change to standard form

[tex](x-4)^{2}+(y-0)^{2}=(\sqrt{10})^{2}[/tex]

Standard form of the equation of a circle is

[tex](x-h)^{2}+(y-k)^{2}=r^{2}[/tex]

Here the r is the radius of the circle and (h,k) is the center

So,

Center = (4,0)

Radius = [tex]\sqrt{10}[/tex]

Hence, if the equation of the circle is [tex]x^{2} +y^{2}-8x+6=0[/tex] then the center and radius of the circle is (4,0) and [tex]\sqrt{10}[/tex] respectively.

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HELP FOR BRAINLIEST! A rectangle solid has a length of 16, a width of 20 and a total surface area of 4480. What is the total surface area of a similar rectangular solid with a width of 10?

Answers

The answer is 3094 units

the angle of elevation to the top of a building in new york is 12° from the ground and 1 mile from the base of the building.

Answers

The height of the building is 1122.528 feet.

Angle of elevation:

Angle of elevation means an angle between the horizontal plane and oblique line from the observer's eye to some object above his eye.

Given,

The angle of elevation to the top of a building in New York is 12° from the ground and 1 mile from the base of the building.

Here we need to find the height of the building.

We know that,

The expression for the height of the building is,

h = tanΘ × x

Where the value of

tan Θ = 12°

x = 1 mile

So, When we apply the value on the formula,

The we get,

h = tan 12° x 1

So, apply the value of tan 12 degree,

h = 0.2126 x 1

h = 0.2126 mile

Simplify the above equation using the information

1 mile = 5280 ft.

That is equal to

h = 1122.528 feet.

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the federal helium reserve held about 20 billion cubic feet of helium in 2010 and is being depleted by about 1.9 billion cubic feet each year. a . give a linear equation for the remaining federal helium reserves in billions of cubic feet, r , in terms of t , the number of years since 2010. r ( t )

Answers

The linear equation for the remaining Federal Helium Reserves, r(t) = 20 -1.9t

There is 20 billion cubic feet of Helium in 2010. Helium is depleted by about 1.9 billion cubic feet each year.

Let 'r' denotes the remaining Federal Helium Reserves in billions of cubic feet.

Let 't' denotes the number of years since 2010.

We have to find a linear equation to represent the depletion of Helium through years since 2010. A linear equation will have two variables, one dependent and one independent variable. Here, let 'r' be the dependent variable and 't' be the independent variable.

Then the amount of Helium depleted in 't' years = 1.9t

So, the remaining Helium in the Federal Helium Reserve since 2010 = 20 - 1.9t.

Thus, r(t) = 20 - 1.9t

This is a linear equation because it depends on only one variable, 't'.

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For what value of k does the equation 2x^2 − 6x + k = 0 have exactly one solution?

Answers

Answer:

k = 2.25 or  9/4

Step-by-step explanation:

2x^2 - 6x + k = 0

2(x^2 - 3x + 2.25) = 0

x                 -1.5

x                 -1.5

-------------------------------------

(x - 1.5) (x - 1.5) = 0

x = 1.5 or 15/10 = 3/2

one solution

identity the restrictions on the domain of f(x)=x-1/x+4

Answers

Answer:

Answer is option A.

X cannot be equal to -4

If ∠DEG is 8 times m∠FEG, what is m∠DEG?

Answers

Answer:

160

Step-by-step explanation:

180 (a straight angle's degrees) /9 = 20

20 * 8 = 160

Check:

160 + 20 = 180

question 12(multiple choice worth 1 points) (04.01 lc) which set of ordered pairs represents a function? {(0, 1), (1, 3), (1, 5), (2, 8)} {(0, 0), (1, 2), (2, 6), (2, 8)} {(0, 0), (0, 2), (2, 0), (2, 4)} {(0, 2), (1, 4), (2, 6), (3, 6)}

Answers

The set of ordered pairs that represents a function is: {(0, 2), (1, 4), (2, 6), (3, 6)}

We know that a function defines a relation between input and output values.

In function for each input there is exactly one output.

We need to find the set of ordered pairs that represents a function.

We need to find the set of ordered pairs such that for each x value (x coordinate) there is unique y value (y coordinate).

1) {(0, 1), (1, 3), (1, 5), (2, 8)}

This set of ordered pairs cannot be a function.

As for x = 1, there are two output values 3 and 5.

2) {(0, 0), (1, 2), (2, 6), (2, 8)}

This set of ordered pairs cannot be a function.

As for x = 2, there are two output values 6 and 8.

3) {(0, 0), (0, 2), (2, 0), (2, 4)}

This set of ordered pairs cannot be a function.

As for x = 0, there are two output values 0 and 2.

and for x = 2, the output values are 0 and 4.

4) {(0, 2), (1, 4), (2, 6), (3, 6)}

This set of ordered pairs represents a function.

Here, for each input value there is unique output value.

Therefore, the set of ordered pairs that represents a function is: {(0, 2), (1, 4), (2, 6), (3, 6)}

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Ryan has a points card for a movie theater.
• He receives 85 rewards points just for signing up.
• He earns 7.5 points for each visit to the movie theater.
.
• He needs 160 points for a free movie ticket.
Write and solve an equation which can be used to determine v, the number of visits
Ryan must make to earn a free movie ticket.

Answers

Answer:

anaaaa

Step-by-step explanation:

85+7.5v=160
7.5v=160-85
7.5v=75
V=75/7.5
V=10
Ryan would need to take 10 visits to get a free ticket.

in a certain school, course grades range from 0 to 100. adrianna took 4 courses and her mean course grade was 90. roberto took 5 courses. if both students have the same sum of course grades, what was roberto’s mean?

Answers

Average of 5 courses is 72

• In simple words, average is the number which is the representative of the list of the numbers.

• Average of numbers is calculated by the sum of the numbers divided by total numbers.

We are given that

Number of courses took by Adrianna = 4

Average of her course grade = 90

Number of course took by Roberto = 5

We also know that , Both students have the same sum of course grades

Let the average of Roberto be x

Average = Sum / Total Subjects

Sum = Average * Total Subjects

So,

90 * 4 = x * 5

x = 360/5

x = 72

Therefore, average of Roberto is 72

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The function h is defined by the following rule.
h(x) = -2x-5
Complete the function table.
X
-4
0
2
3
5

H(x)
?
?
?
?
?

Answers

h(x)= -2(-4)-5=3
h(x)= -2(0)-5=-5
h(x)=-2(2)-5=-9
h(x)= -2(3)-5= -11
h(x)= -2(5)-5= -15

if i choose four cards from a standard $52$-card deck, with replacement, what is the probability that i will end up with one card from each suit?

Answers

The probability that i will end up with one card from each suit is 3/32.

Probability:

Probability refer the possibility of the event.

The formula for the probability of the event is,

Probability of event to happen P(E) = Number of favorable outcomes/Total Number of outcomes

Given,

If i choose four cards from a standard 52-card deck, with replacement,

Then we need to find the  probability that i will end up with one card from each suit.

In the first draw, we can take one card, if it is a spade one,

Then for the second draw we have 39 options

For the third draw we have 26 options

For the fourth draw we have 13 options,

So, the probability that i will end up with one card from each suit is

=> 1 x 39/52 x 26/52 x 13/52

=> 1 x 3/4 x 1/2 x 1/4

=> 3/32

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Pqrs and t are on line k such that q is the midpoint of pt, r is the midpoint of qt, and s is the midpoint of rt. If ps

Answers

Given the midpoint, the value of PT will be 10 2/7.

How to calculate the value?

Q is the midpoint of PT,

so PQ = QT.

R is the midpoint of QT,

so QR=RT.

S is the midpoint off RT,

so RS=ST.

Let us say RS = ST = x .

Then, RT= RS + ST= x + x = 2x ,

so RT = QR = 2x

Then, QT = QR+RT = 2x+2x = 4x ,

and PQ = QT = 4x .

Then, PS= PQ+QR+RS=4x+2x+x=7x ,

and PT=PQ+QT=4x+4x=8x

The problem says that PS = 9

Therefore, 7x = 9 and x = 9/

PT = 8x = 8 × 9/7 = 10 2/7.

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P, Q, R, S, and T are on line k such that Q is the midpoint of segment PT, R is the midpoint of segment QT, and S is the midpoint of segment RT. If segment PS = 9, then what is PT?

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