pretreatment of colitic mice induced by dextran sulfate sodium (dss) with tff2 reduces expression of vascular cell adhesion molecule 1 (vcam-1), an adhesion molecule that mediates leukocyte recruitment

Answers

Answer 1

Due to its anticoagulant qualities, dextran sulfate sodium (dss) decreases the formation of vascular cells.

Dextran sodium sulfate (DSS), a pharmacologic colitogen with anticoagulant characteristics, is used to elicit illness in the most used mouse model of colitis. DSS is a negatively charged, water-soluble sulfated polysaccharide with such a molecular weight range of 5 to 1400 kDa. The use of 40–50 kDa DSS in drinkable water causes the most severe mouse colitis, which most strongly matches human UC. Although the exact method by which DSS causes intestinal inflammation is unknown, it is most likely the outcome of damage to the large intestine's epithelial monolayer, which allows proinflammatory intestinal contents, such as bacteria and their products, to spread into underlying tissue.

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Related Questions

In humans, mitochondrial genetic disorders are inherited from only the mother. The severity of such diseases can vary greatly, even within a single family. What form of inheritance does this represent?.

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In humans, mitochondrial genetic disorders are inherited from only the mother. The severity of such diseases can vary greatly, even within a single family. This form of inheritance represents cytoplasmic inheritance.

In the field of genetics, we can describe cytoplasmic inheritance as a kind of inheritance where genes that are present in the cell, other than the nucleus, are transmitted from the parent to the offspring.

In humans, mitochondria are the organelles known to have their own genetic material.

During fertilization, the mitochondria found in the male sperm are destroyed by the egg cell present in the female body.

Hence, mitochondrial genes are transferred to an offspring from the mother only. Any kind of disorders or diseases linked to the female mitochondrial genes has the probability to be passed on to the offspring.

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some species of bacteria can live in hot springs. their cells contain enzymes that function best at temperatures of 70c or higher.

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The enzymes will not increase the rate of reactions as much as they would at 70°C

Enzymes are biological catalyst that help in speeding up a reaction. Although most enzymes function best at normal temperatures, there are many others which work best at higher or lower temperatures. Temperature plays an important role for the proper working of an enzyme.

An enzyme that functions best at 70 degrees Celsius will increase the rate of a reaction by maximum amount is this temperature will be provided to it. It's activation energy will be maximum at this temperature.

However, if the temperature is lowered for this enzyme, then it will not be able to speed up the rate of reactions with the same intensity.

Although a part of your question is missing, you might be referring to this question:

Some bacteria live in hot springs. Their cells contain enzymes that function best at temperatures of 70°C or higher. At a temperature of 50°C, how will the enzymes in these bacterial cells most likely be affected?

A. The enzymes will be destroyed by lysosomes.

B. The enzymes will lose their bond structure and fall apart.

C. The enzymes will require less energy to function than at 70°C.

D. The enzymes will not increase the rate of reactions as much as they would at 70°C.

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How does the law of conservation apply to nutrient cycles?

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Answer:

Matter can change form through physical and chemical changes, but through any of these changes matter is conserved. The same amount of matter exists before and after the change—none is created or destroyed. This concept is called the Law of Conservation of Mass

Explanation:

in a specific ecosystem, the population with the greatest number of members will be the secondary consumers.

Answers

False. in a specific ecosystem, the population with the greatest number of members will be the producers

Producers are organisms that create food in the food chain and are found at the bottom of the food chain pyramid. Producers use sunlight to fix CO2 and H2O, which they accumulate in their bodies as biomass and use to provide energy to other organisms in the food chain.

Food chains do not exist naturally without producers. In some cases, it depicts an upright pyramid, but in others, it depicts a spindle-shaped pyramid in a separate ecosystem.

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the muscular tube between the stomach and the large​ intestine, divided into the​ duodenum, the​ jejunum, and the​ ileum, is​ the:

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The muscular tube between the stomach and the largeintestine, divided into the​ duodenum, the​ jejunum, and the​ ileum, is​ the small intestine.

What is alimentary canal?

The alimentary canal is a muscular hollow continuous tubular organ that begins at the mouth and ends at the anus and is in charge of digestion and absorption of ingested food and liquids.

The alimentary canal, also known as the alimentary tract, is a component of the digestive (gastrointestinal) system.

The small intestine is the muscular tube that connects the stomach to the large intestine and is divided into the duodenum, jejunum, and ileum.

Thus, the answer is small intestine.

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automated segmentation of human axon and myelin from electron microscopy data using deep learning for microstructural validation and simulation

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When axon and myelin are separated from nervous system microscopy pictures, useful quantitative information about the tissue's microstructure, including axon density and myelin thickness, is obtained.

What is Myelin and axon ?

Myelin is a lipid-rich substance that surrounds nerve cell axons, the "wires" of the nervous system, to insulate them and speed up the transmission of electrical impulses (known as action potentials).

In your brain, each neuron has a single, lengthy cable that extends from the cell's core. An axon is a cable that is much thinner than a human hair and is where a neuron's electrical impulses leave the cell to be picked up by neighbouring neurons.

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what virus only affects bacteria

Answers

Answer: Bacteriophages (phages)

Explanation:

cells in the body exist in an aqueous environment. they are constantly surrounded by water or a solution that contains water.

Answers

Answer:

A solution that contains water

Explanation:

it contains 90% water however it still contains other forms of liquids and stuff

identify the mass above which a man whose height is 185 cm would be classified as obese

Answers

Answer:

Around 90.7

Explanation:

Difference between plants and animal In terms of feeding​

Answers

Answer:Plants

Explanation:animals

Brown-eyed alma has a blue-eyed mother and a brown-eyed father. In this case, her brown eyes were determined by a _____ allele.

Answers

Her brown eyes in this case were caused by a dominant allele.

What are dominant alleles, exactly?When more than one allele is present, a dominant allele is a gene variant that will still cause a particular phenotype.A dominant allele typically codes for a functional protein.The allele is dominant because it produces enough enzyme from a single copy to allow a cell to have an abundance of a certain product.Why are some genes dominant alleles?A dominant allele is referred to as dominant because it conceals the recessive trait and appears in the phenotype of a heterozygous species.One allele is all that is required to express the trait.

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copper amalgam used for filling primary teeth may impart a(n) color. group of answer choices bluish-black orange bluish-green brown

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Copper amalgam used for filling primary teeth may impart a bluish green color.

In dentistry, copper alloy mixture is indispensable for tooth decay due to chemical and physical characteristics.

Copper amalgam - an alloy of copper that is composed of 22–32% silver,  8% zinc, 50% mercury and 14% tin.

Traditionally, copper along with silver and tin has immense importance as a dental alloy.

It enhances the compressive strength of the filling material and setting contraction as well.

Generally, amalgam of copper is used for filing tooth and is most effective, sound and safe treatment for tooth cavities.

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In order for an experiment to be considered a "controlled experiment" the experiments must
be exactly the same except for how many variables?

Answers

Answer:

one

Explanation:

only one variable can be changed in an experiment to be able to tell if what you changed made the experiment change.

How is the nuclear membrane like the cell membrane?

Answers

Answer:

because they have similar

Explanation:

functiona and stucture

Answer:

So basically, the critical function of the nuclear membranes is to act as a barrier that separates the contents of the nucleus from the cytoplasm. Like other cell membranes, the nuclear membranes are phospholipid bilayers, which are permeable only to small nonpolar molecules.

Hope this helps!

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human neural stem cell transplants to address multiple pathologies associated with traumatic brain injury.

Answers

For traumatic brain injury (TBI), neural stem cell (NSC) transplantation is a potential option

What is traumatic brain injury?

TBI is a change in brain function brought on by an outside stimulus and showing signs of brain pathology. It might result from a hit to the head, a blast, a jolt, or a bump, even one that penetrates the skull. Due to its financial consequences, TBI is a public health issue on a global scale. The majority of TBIs are treatable, do not require hospitalization, but they can affect productivity. The majority of TBI care expenses are attributable to a lower percentage of TBI caused by falls or penetrating TBI (PTBI), which necessitates hospitalization.

Why human neural stem cell transplant was considered beneficial for TBI

For traumatic brain damage, neural stem cell (NSC) therapy is a potential option (TBI). Mesenchymal stem cells (MSCs) have also been researched as a potential TBI treatment because of their roles in brain regeneration and neurotrophic effects. In the current investigation, autologous MSC-derived NSC-like cell transplantation in 10 patients with severe TBI was examined for safety, viability, and biological effects. All the patients had physical and neurological examinations, standard laboratory testing, and evaluations of the results of neuroradiological studies after receiving intravenous or intrathecal injections of human NSC-like cells. The findings showed that most patients had, to varying degrees, improved neurological function during the follow-up period. Following transplantation, no patient experienced any mortality or severe adverse effects.

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the approach allows for the scientific study of the interrelationship between culture and what humans have inherited genetically.

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Biocultural is the approach that allows for the scientific study of the interrelationship in between the culture and what the humans have inherited genetically

Biocultural is the approaches recognize the pervasiveness and the dynamism of the interactions between the biological and the cultural phenomena, and they was explicitly strive to the integrate the biological, sociocultural, the environmental, and other kinds of the data For example, the biocultural anthropologist might study that how the food we eat shapes to our societal and structure and that influences the politics and how they changes in the nutrition and the availability of food affect the health of the average persons life

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What molecule is the source of the protons that are used to establish the proton gradient?.

Answers

Answer:.

Explanation:

Answer:

Water.

Explanation:

Through photosystem II, energy that is derived from the absorption of protons splits water molecules into oxygen and protons. The reaction takes place in the thylakoid lumen, thus, the release of protons from water will establish a gradient across the membrane.

Hope this helps.

Complete this hypothesis statement:
If a plant receives more water,

Answers

It dies due to over accumulation of water in the plant’s tissue

the pizza that you ate for lunch is being digested. summarize what happens to it in your stomach.(1 point)

Answers

I ate a pizza, which my stomach then churned and mixed with gastric acid and digestive enzymes.  

What happened after I ate the pizza? Summarize. 

Despite a few exceptions, the most of pizza's include a lot of calories, sugar, and sodium. They frequently have excessive fat, extra sugar, and artificial preservatives. They are also heavily processed.

French bread style and packed crust varieties can add even more calories, as can selecting toppings like sausage, additional cheese, and other high-calorie foods.

The stomach is a digestive system organ that stores and processes food. It is situated between the intestine and the esophagus. After passing through the esophagus, the food enters the stomach, where it is digested to remove the nutrients with the aid of the digestive enzymes and gastric acid released by the stomach.

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Answer:

I have that same question on my bio assignment also... but i think the answer is "the pizza is churned, mixing it with digestive enzymes and gastric acid?

Explanation:

endangered species with very small populations are especially at risk of loss of genetic diversity due to: mutation genetic drift natural selection immigration

Answers

endangered species with very small populations are especially at risk of loss of genetic diversity due to immigration

In the biological terms, the immigration was means new organisms joining or entering the different population. These new organisms are would bring with them the new alleles or the new genes to be the existing population. It would be result in the genes transfer. the Genes transfer refers to the the movement of the genetic material between the organisms

For example, the salmon start life in the rivers and to migrate to the sea to feed and then grow. After then spending up to seven years in the ocean, they may migrate back to the rivers and they were born in so that they can be spawn.

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we initially reasoned that conventional fluorescently-labeled antibodies could potentially be used in exm if a sufficient number of linkages could be formed between the antibodies and hydrogel so that protease-digested antibody fragments would remain linked to the hydrogel (fig. 1).

Answers

Expansion Microscopy (ExM), an ultra microscopy method that employs physical expansion of fixed specimens to enable features closer than the diffraction limit of light (250 nm) to become resolvable in the expanded specimen, was recently developed by Boyden and colleagues.

Fluorophores on fixed specimens are connected to a swellable polymer that is physically stretched to permit super-resolution microscopy with conventional microscopes. This technique, called expansion microscopy, has only recently been developed. We have created and described novel techniques for attaching fluorophores to the polymer, making it possible to use traditional fluorescently-labeled fluorescent proteins and antibodies for expansion microscopy. Our techniques will help the approach spread quickly and will simplify the process and broaden the range of appropriate labels.

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If aspartate was linked to amino acids lysine, tyrosine, and serine, would this tetrapeptide be which of the
following?

Amphipathic

Hydrophobic

Cannot be determined from information given

Hydrophilic

Answers

If aspartate was linked to amino acids lysine, tyrosine, and serine, this tetrapeptide would be hydrophilic; option D.

What are amino acids?

Amino acids are the basic monomer units from which proteins are made.

Amino acids consists of the following general parts:

a central carbon atoman amino groupan R groupa carboxyl groupa hydrogen atom

The R groups of amino acids determines the nature and polarity of amino acids.

The R groups of the amino acids aspartate, lysine, tyrosine, and serine are all polar groups.

Therefore, the tetra peptides formed from the amino acids will be hydrophilic.

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the organs for taste receptors are called , most of which are found associated with .

Answers

The organs for taste receptors are called taste buds papillae.

What are taste buds papillae?

They are known as papillae and the majority of them have taste buds. The tiny hairs on taste buds, known as microvilli, are extremely sensitive (say: mye-kro-VILL-eye). You can tell if something is sweet, sour, bitter, or salty because those little hairs communicate with the brain about how it tastes.

On the upper surface of the tongue, soft palate, upper esophagus, cheek, and epiglottis are little structures called as papillae that house the taste receptors. The five components of taste perception—saltiness, sourness, bitterness, sweetness, and umami—are detected by these structures.

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Any tissues that exist in layers and form linings or coverings fall into the category of.

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Stratified epithelia are any tissues that appear in layers and establish linings as well as coverings.

The epithelium is a type of body tissue that surrounds all of the internal and external surfaces of your body, tracks body cavities and hollow body organs, and serves as the main tissue in glands. Epithelial tissue serves a variety of functions in your body, such as protection, secretion, and absorption.

Epithelial tissue is made up of stratified epithelial cells. Cells can be of different shape and structured in a single layer or multiple layers depending on their position in one's body or their functions.

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4. Which characteristic of life should be the title of this graph?
A. Cellular Basis
B. Growth
C. Homeostasis
D. Reproduction​

Answers

The characteristic of life which fit the title of this graph is homeostasis.

Option c is the correct answer choice.

This goes to say that all living organisms share a similar characteristics such as homeostasis

Be that as it may, it is very important that living things maintain a stable internal environment. This homeostasis in particular means the mentainance of a fairly internal environment of an organism

Characteristics of living organisms

Living things be it plants or animals share a number of key characteristics or functions such as:

MovementRespirationHomeostasisReproductionGrowth EvolutionCompetitionExcretion

Complete question:

Which characteristic of life should be the title of this graph?

A. Cellular Basis

B. Growth

C. Homeostasis

D. Reproduction

The graph is attached is attached to the question

So therefore, the characteristic of life which fit the title of this graph is homeostasis.

Option c is the correct answer choice.

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PLEASE HELP!!
What do all living organisms contain?

Answers

Answer: cells

Explanation:

Answer:

All living organisms contain cells

What are the structures and stage of mitosis?

Answers

Today, mitosis is understood to involve five phases, based on the physical state of the chromosomes and spindle. These phases are prophase, prometaphase, metaphase, anaphase, and telophase.

Prophase, prometaphase, metaphase, anaphase, telophase

prior to the work of blank, scientists did not distinguish between members of the archaea and the bacteria.

Answers

Prior to the work of Carl Woese, scientists did not distinguish between members of the archaea and the bacteria.

What is Carle woese famous for ?

Microbiologist Carl Woese made significant contributions to phylogenic taxonomy. Prokaryotic and eukaryotic were the first two domains on the tree of life, however Woese challenged this idea using ribosomal RNA (rRNA)

It was proposed that these species were as unrelated to bacteria as bacteria are to eukaryotes in a 1977 paper published by Woese and his postdoctoral fellow George Fox in the Proceedings of the National Academy of Sciences.

The way Woese used to identify this "third form of life," comparing the sequences of one specific molecule essential to cellular function, called ribosomal RNA, has since become the norm for identifying and categorising all species.

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why does the body need to use energy for this process

Answers

I believe the answer is C or D because ATP as a source of energy, sodium is extruded from the cell and potassium is inviting in

Hope this helps

the bacterial flagellum moves multiple choice by rotation that is powered by atp. by rotation that is powered by the proton motive force. in a wave-like fashion that is powered by atp. in a wave-like fashion that is powered by the proton motive force.

Answers

The bacterial flagellum moves (b) by rotation that is powered by the proton motive force.

Flagellum is the motile structure found in many prokaryotic organisms and a few eukaryotic organisms. It is along thread-like structure. It can help organisms in moving or swimming. An organism may have a single flagellum or may have multiple flagella.

Proton motive force (pmf)is the force generated due to the pumping of the protons across the plasma membrane. In mitochondria, this force aids in the production of ATP. There are two components of pmf are:  membrane potential (ΔΨ) and the gradient of proton concentration (ΔpH).

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Stop light A changes color every 45 seconds and Stop light B changes color every 80 seconds. Both Stop lights just changed. After how many seconds will the stoplights change color at the same time? Explain why gases are compressible, but solids and liquids are not. Click here to read and refer to "An Occurrence at Owl Creek Bridge" by Ambrose Bierce in order to answer the questionbelow.Which is an example of an internal conflict from the story?O Peyton daydreams what it would be like to be free.O Peyton wonders if he can swim ashore or not.O Peyton is sorry for setting fire to the bridge.O The lieutenant cannot get his men to shoot Peyton. A salesperson sold a pick-up for $18,760. They were paid a 4.5% commission. How much money were they paid? This table represents function f. If function g is a quadratic function that contains the points and , which statement is true over the interval ? A. The average rates of change of f and g cannot be determined from the given information. B. The average rate of change of f is less than the average rate of change of g. C. The average rate of change of f is the same as the average rate of change of g. D. The average rate of change of f is more than the average rate of change of g. How did conquests in america change Spain? A piece of machinery depreciates at a fixed rate of 12% per year for 7 years. If the machinery is valued at $100,000 after 7 years, how much would the machinery have initially cost rounded to the nearest dollar?a.$113,636d.$45,235b.$40,868e.$244,692.86c.$244,693 Which of these is TRUE?A. DNA must unwind before it can replicate.B. Ribosomes control DNA replication.C. DNA replication occurs outside the nucleus.D. DNA replication only occurs once per day. What is the most likely meaning of exercise in the following sentence? If you participate in a peaceful protest, you exercise the right to have freedom of speech. A. risk B. ensure C. understand D. put into practice How would knowing about the climate of a region help you determine the vegetation of a place? 2) "an author ought to write for the youth of his generation, the critics of the next, and the schoolmasters of ever afterward." What did Raya do wrong? Use complete sentences to describe her mistake. A string of length L , mass per unit length , and tension T is vibrating at its fundamental frequency. (ii) If the mass per unit length is doubled, with all other factors held constant, what is the effect on the fundamental frequency? Choose from the same possibilities as in part (i). 3.Section 21. Write the names of places in the diagram below to describe how the bubonicplague spread in the 14th century.1. The plague probablyoriginated inCentral Asia.It traveled alongtrade routes toIt spread northand west to2.4.It was carriedon a ship to Find f '(a).f(x) = [tex]\frac{1}{\sqrt{x} +5}[/tex] Which of the following with Alexander Hamilton support?A) promoting our culture as the most important economic activity within the United StatesB) reducing the power of the central governmentC) promoting manufacturing and commerce to improve the economyD) Aiding France during the French revolution 6) Complete the following concept map.PositiveAtomNeutronsElectron clouds gerber product's gerber mixed cereal for baby contains, in each serving, 60 calories and 11 grams of carbohydrates. gerber mango tropical fruit dessert contains, in each serving, 80 calories and 21 grams of carbohydrates. if you want to provide your child with 300 calories and 74 grams of carbohydrates, how many servings of each should you use? gerber mixed cereal for baby serving(s) gerber mango tropical fruit dessert serving(s) Solution a has a hydrogen ion concentration of 3. 2 x 10-9 and solution b has a hydrogen ion concentration of 6. 9 x 10-5. Which solution is more basic?. helen frankenthaler's painting mountains and sea could easily be seen as rather than a landscape.