The mechanisms of metastasizing breast cancer are complex. the goal was to identify tumor-induced stromal modifications that affect metastatic cell behavior, and function as better marks for therapy.
Dual-species gene expression analysis was performed to identify stromal changes in cancer-bearing tissue for three different metastatic Breast cancer xenografts. In pre-clinical models of Breast cancer, the systemic need for S100A8+ myeloid cells-including myeloid-derived suppressor cells (MDSCs)-was stimulated by tumor-derived factors.The need for S100A8+ myeloid cells was reduced by inhibition of tumor-derived factors leading to fewer metastases and fewer primary tumors. Those myeloid-derived suppressor cells possess the ability to suppress T cell accumulation upon co-culture.
The release of macrophage inhibitory factors activates the need for S100A8+ myeloid cells systemically. Inhibition of MIF leads to delays in lower metastatic burden and tumor growth. In enhancing cancer progression independent of their suppressive activity on T cells, there is the recruitment of S100A8+ myeloid cells to secondary sites in xenograft models and primary tumors of Breast cancer.
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a simple three-item questionnaire and psa level can help distinguish luts secondary to bph vs those with other causes7
Benign prostatic hyperplasia is a complex disease that is progressive in many men.
Benign prostatic hyperplasia is regularly associated with symptoms of the lower urinary tract, acute urinary retention (AUR), and BPH-related surgery are some of the complications of such a disease. It is necessary to fo the men identify the increased risk of Benign prostatic hyperplasia procession to optimize therapy. Many factors are involved in a such progression such as prostate volume, age, and so on. Serum prostate-specific antigen level is correlated to prostate volume, which makes it easy to determine the risk of the progression. For Benign prostatic hyperplasia, medical treatments are mostly used treatment. Alpha-blockers grabbed the instant symptom relief but didn't reduce the risk of Benign prostatic hyperplasia surgery. the 5-alpha-reductase inhibitors affect the disease and reduced the prostate volume, which leads to improved symptoms and reduced the risk of Benign prostatic hyperplasia surgery and AUR. Combination therapy is more beneficial than monotherapy, there were the result of symptom improvement with such therapy
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a deadly embrace: hemagglutination mediated by sars-cov-2 spike protein at its 22 n-glycosylation sites, red blood cell surface sialoglycoproteins
A Deadly Embrace: Hemagglutination Mediated by SARS-CoV-2 Spike Protein at Its 22 N-Glycosylation Sites, Red Blood Cell Surface Sialoglycoproteins, and Antibody is a research paper by David E. Scheim.
What is the abstract?The characteristics of various enveloped virus strains dating back to foundational results from the 1940s are highlighted by rouleaux, or stacked clusters, of red blood cells (RBCs), which were found in the blood of COVID-19 patients in three studies. The following are important examples for COVID-19: Although ACE2 is the target for SARS-viral CoV-2's fusion and replication, SARS-CoV-2 initially attaches to sialic acid (SA) terminal moieties on host cell membranes via glycans on its spike protein; however, hemagglutinin esterase (HE), an enzyme that releases these glycan-mediated bindings to host cells, is expressed among betacoronaviruses in the common cold strains but not by SARS-CoV, SARS-CoV-2 and MERS.
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if phosphorous concentrations were to suddenly increase in a marine ecosystem, which of the choices would likely occur?
If phosphorus concentrations suddenly increased in a marine ecosystem, then primary productivity will also increase.
Ecosystem A biotic community along with its abiotic environment together form an ecological system or ecosystem. Tansley introduced the term "ecosystem" in 1935.An ecosystem is a self-regulating, self-sustaining structure that serves as a functional unit of the biosphere. It is made up of a community of living things and their physical surroundings, and it is this community that interacts and exchanges materials.The essential functions of ecosystem function include:productivitydecompositionenergy flownutrient cyclingProductivity:It is defined as the rate of biomass production.
Primary productivity:It is referred to as the quantity of biomass or organic matter created by plants during photosynthesis per unit of area over time.
It is divided into:
Gross primary productivity Net primary productivity.Hence, the correct answer is that the primary productivity increases.
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conifer leaves are generally thin and needle-like, while seeds are contained in cones. conifers include blank and blank
Conifer leaves are generally thin and needle-like, while seeds are contained in cones. Conifers include pine and cedar.
One of the most familiar and particular characteristics of this group of plants is that they are 'evergreen plants'.
They belong to the class of gymnosperm plants and exhibit secondary growth properties. Outer appearance shows that they are straight, long and pointy end plants having woody stems and trunks.
Their bark has horizontal round circles and their internal structure becomes complex as they grow older.
Moreover, the trees of this group are also covered with blades, scales and wedges along with a waxing coating that prevents water loss from the leaves.
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omip-069: forty-color full spectrum flow cytometry panel for deep immunophenotyping of major cell subsets in human peripheral blood
For detailed immunophenotyping of the primary cell subsets found in human peripheral blood, a 40-color flow cytometry-based panel was created.
What is 40-color flow cytometry?When several different types of testing must be conducted on a single sample or timepoint, sample availability is frequently constrained, especially in the case of clinical trial material. In addition to providing a more thorough assessment of the immune system, maximizing the quantity of information that can be gleaned from a single sample helps to solve the problem of restricted sample availability. CD4 T cells, CD8 T cells, regulatory T cells, T cells, NKT-like cells, B cells, NK cells, monocytes, and dendritic cells are all identified in the panel.Learn more about the Flow cytometry with the help of the given link:
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lung tissues make the
lung organ,____
tissue make the pancreas
organ
Lung tissues make the lung organ, exocrine tissue makes the pancreas organ.
Explanation:Almost all of the pancreas (95%) consists of exocrine tissue that produces pancreatic enzymes for digestion. The remaining tissue consists of endocrine cells called islets of Langerhans. These clusters of cells look like grapes and produce hormones that regulate blood sugar and regulate pancreatic secretions. The pancreas is invested by a very thin connective tissue capsule and divided into lobules, which in turn are formed from dense accumulations of exocrine glands that often surround islets of Langerhans.
based on the matrix, which tree represents the most parsimonious explanation of relatedness among these species?
Based on the matrix Phylogeny 2 tree represents the most parsimonious explanation of relatedness among these species
The study of relationships and the evolutionary history of various groupings of species is known as phylogeny. The goal of phylogeny is to reconstruct the evolutionary course of all species on Earth. It is based on the phylogenetic theory, which holds that all living things descended from a single common ancestor. A phylogenetic tree is a visual representation of how species are related to one another. The comparison of genetic and anatomical similarities shows that relationships are based on shared traits.
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Plants make sugar through photosynthesis, but they don't need that sugar
for anything. True or false
Answer:
False
Explanation:
Answer:
False!
Explanation:
They need it to make glucose!
IS NEEDED ASAP PLEASE HURRY
The number of snails in a given Alabama creek bed by each of 30 segments of the creek is as follows:
32, 6, 21, 10, 8, 11, 12, 36, 17, 16, 15, 18, 40, 24, 21, 23, 24, 24, 29, 1, 4, 9, 32, 23, 40, 15, 29, 25, 33, 20
What is the median number of snails of the 30 segments of this Alabama creek?
Question 6 options:
24
23
21
Answer: Median is 21
Explanation:
In thick skin, what do the Dermal Papilla produce?
In thick skin, the dermal papilla produce the hair shaft.
What is a dermal papilla?The dermal papilla is a finger-shaped structure that will be found in an area where the dermis interdigitates with the epidermis. In the dermal papillae we will find blood vessels that will nourish the hair follicles, carrying nutrients to the deepest layers of the epidermal cells.
The dermal papillae are found in the outermost layer of the dermis, called the papillary dermis. Having a role in the formation and growth of hair.
Therefore, we can confirm that in thick skin, the dermal papilla produce the hair shaft.
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anaphylaxis caused by stinging insects is typically an allergic reaction to rather than the bite or sting itself.
Anaphylaxis caused by stinging insects is typically an allergic reaction to the injected poison, irritating toxin, and deadly venom rather than the bite or sting itself. The correct answer is option(D)i.e, All of these answers are correct.
Anaphylaxis can be fatal if untreated or improperly treated. Even if your symptoms disappear pretty quickly, they may return a few hours later, worsen, and become more challenging to cure.
People who have allergies typically experience mild to moderate symptoms, such as watery eyes, a runny nose, or a rash. Anaphylaxis, a serious allergic reaction that can be fatal, can however occasionally result from exposure to an allergen. When too many chemicals are released at once, shock results, which is a severe reaction
The most frequent triggers within these groups were wasp and bee stings (n = 1460 and 412, respectively), legumes (n = 241), animal proteins (n = 225), and analgesics (n = 277). In children, peanuts, cow milk, and hen's eggs were the most common food allergens to cause anaphylaxis; in adults, it was wheat and shellfish. When you have anaphylaxis, your immune system releases a rush of chemicals that can put you in shock and cause your blood pressure to drop and your airways to constrict.
The complete question is:
Anaphylaxis caused by stinging insects is typically an allergic reaction to ____________ rather than the bite or sting itself.
A. injected poison
B. irritating toxin
C. deadly venom
D. All of these answers are correct
What do you notice is the main difference between the structure of the connective tissues and the structure of the epithelium? make sure to note the organization of cells in these two tissue types. How does this structure relate to function?.
Epithelial tissue lines the cavities and surfaces of organs and blood arteries throughout the animal body, whereas connective tissue supports, links, and divides many types of tissues and organs in the body. This is the main distinction between epithelial and connective tissue.
Cell arrangement: The physical properties of the Epithelial tissue affect how the connective tissue is organized. There are different arrangements of epithelial cells, such as squamous, cuboidal, and columnar, that organize as simple, stratified, pseudostratified, and transitional. Since epithelial cells form from ectoderm, mesoderm, and endoderm, this explains why epithelia line body cavities. Dense irregular connecting tissue is made up of messily organized tightly packed collagen bundles.
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fungi question 17 options: 1) absorb nutrients from the environment. 2) take in food by phagocytosis. 3) generate atp and reducing equivalents by photosynthesis.
D.) Fungi absorb nutrients from the environment.
Fungi- Fungi can be either single-celled creatures or extremely complex multicellular ones. Although they can be found practically anywhere, most of species prefer to reside on land, primarily in dirt or on plant materials, as compared to the ocean or fresh water. The decomposers, a class of organisms that grow in the dirt or on decomposing plant matter, have a substantial impact just on cycling of carbon and other substances.
Organism- An organism is a collection of molecules working together to form a more or less stable whole that demonstrates the characteristics of life.
The given question is incomplete, please find below the complete question,
Q. Fungi ________.
A) Absorb nutrients from the environment
B) Take in food by phagocytosis
C) Generate ATP and reducing equivalents by photosynthesis
D) All of the choices are correct.
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Nitrogen is also cycled through living organisims
True or False
Answer:
True, death and decay of dead animals and also excretion cycles nitrogen
The ossicles are the three smallest bones in the human body. please select the best answer from the choices provided t f
The given statement is true that the ear ossicles are the three smallest bones in the human body.
Ossicles, also called auditory ossicles, one of the three small bones in the middle ear of all mammals. These are the hammer or the malleus, the incus or the anvil and the stapes or stirrup. Together they form a short chain that passes through the middle ear and transmits vibrations caused by sound waves from the tympanic membrane to the fluid in the inner ear. The malleus looks more like a club than a hammer, while the anvil looks like a premolar with an extensive root system. The stapes looks a lot like a stirrup. The top or head of the hammer and the body of the anvil are held together by a tight connection and are located in the attic, or top, of the tympanic cavity. The hammer handle attaches to the upper half of the drum diaphragm.
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Evidence 2: A tool impression has been found at the crime scene. Lab technicians have analyzed the impression and have determined that it is from a crowbar that has a chipped right corner of the beak (the split end). A crowbar found at the suspect's home has a similar chip in the right corner of the beak. Is this class or individual?
A crowbar is a metal bar tool with flattened ends at each end, generally with a small crack to aid remove nails or pushing two materials or items apart. It is also referred to as a wrecking bar, gorilla bar, pinch bar, or a pry bar.
Crowbars, pinch bars, and pry bars are hand tools used to pry two items apart. Their flattened, angled end functions as a lever, letting you exert a substantial amount of force between objects.A lever is something like a crowbar.In a lever, the load force is on the opposite side from where a person pushes or pulls and is applied to the side of the thing we are trying to lift or pry apart.Learn more about tool impression here:
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effects of preservatives in pitfall traps for collecting arthropods: a comparison of ethylene glycol and five alternative preservatives
To study arthropods in forests, pitfall traps with ethylene glycol as a preservative are frequently employed.
What does the study of pitfall traps for collecting arthropods indicate?Because ethylene glycol is sweet, there have recently been reports of wild vertebrates damaging pitfall traps. In order to choose an alternate preservative for use in pitfall traps, this study evaluated ethylene glycol with five viable substitutes. The study employed the five substitute preservatives. Depending on the type of preservative employed, different numbers of arthropods were gathered, and distinct arthropod assemblages had varying compositions. The later of the two alternate preservative combinations that were shown to be more effective for collecting arachnids, formalin+bleach and salt water+bleach.Learn more about the pitfall trap with the help of the given link:
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The interference pattern seen when light passes through narrow, closely spaced slits, is due to.
The interference pattern seen when light passes through narrow, closely spaced slits, is due to Diffraction:
Diffraction is a light phenomenon that occurs when light strikes an impediment or travels through the slit. This results in a light pattern known as interference.
When light goes through a slit or hits an object, it creates a series of patterns known as interference patterns. The light bends through the corners of the barriers or passes through a slit that might behave as an obstruction. The pattern is caused by the diffraction phenomenon and involves the form of the slit in it. Diffraction is the sole phenomena that causes interference patterns, rather than reflection, refraction, dispersion, or deflection. Thomas Young's work on limited double-slit geometry produced observable interference effects and was the basis for diffraction.
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rotein synthesis is an essential part of cellular metabolism, and it requires the involvement of a number of molecules, structures, and organelles. list the molecules, structures, and organelles in the order that enables protein synthesis. start with the instructions that encode a protein, and end with the structure through which a protein leaves the cell.
According to the given statement the correct order is
DNA ⇒ RNA ⇒ Ribosomes ⇒ Endocytic reticulum in rough ⇒ Golgi apparatus ⇒ Plasma layer ⇒ Protein Leaves the Cell
What is Ribosome?At a ribosome, an intercellular structure made of both RNA and protein, the process of making proteins happens in a cell. The messenger RNA (mRNA) sequence is processed by the ribosome, which translates the gene sequence into a specific string of amino acids that form extended chains and fold to make proteins.
What roles do ribosomes function?Ribosomes' two major purposes are peptide bond formation and message decoding. These two tasks are carried out by the two large, unequal-sized ribonucleoprotein particles (RNPs) called as the ribosomal subunits. A variety of ribosomal proteins and one or more ribosomal RNAs (rRNAs) make up each subunit (r-proteins)
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Where does energy in the sugar molecules made by photosynthesis come from?
Answer: the sun
Explanation: during the process of photosynthesis, cells use carbon dioxide and energy from the sun to make sugar molecules and oxygen. These sugar molecules are the basis for more complex molecules made by the photosynthetic cell, such as glucose.
Which term describes DNA sequences that code for proteins
- genome
- gene
- regulatory sequences
- non-coding regions
Explanation:
Gene
A segment of a DNA molecule (a sequence of bases) that codes for a particular protein and determines the traits (phenotype) of the individual. A gene is the basic unit of heredity in a living organism.
Enzymes act as_______________ in the body and help ______________ the metabolic processes within the cell. locks, slow down immune factors, protect chemical catalyst, speed up gatekeepers, monitor
Enzymes act as organic catalyst in the body and help in the speed up the metabolic processes within the cell.
Enzymes- An enzyme is a type of biological catalyst that is typically always a protein. It quickens a certain chemical reaction inside the cell. Throughout the procedure, the enzyme is continually used and is not lost.
Amylase, for instance, supports the transformation of carbs into sugars in saliva.
Metabolic Process- Metabolic activities in the body's cells that turn food into energy are referred to as metabolism. Our bodies need this energy in order to move, think, and develop. Specific proteins in the body control the chemical reactions involved in metabolism.
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what are three ways that form ores
There are 3 predominant varieties of ore genesis: inner approaches, hydrothermal strategies, and surficial methods. Ore can accumulate through geologic hobby, such as when volcanoes deliver ore from deep inside the planet to the floor. this is known as an inner system.
Ores are classified based totally on how they shape. a few ores form from the cooling and crystallization of minerals inside magmas, lavas, or igneous intrusions. these are called magmatic or volcanic ores. Nickel, copper, and iron ores are usually fashioned from magmatic or volcanic-related deposits.
Gold minerals form in hot rocks in and around volcanoes. Low sulfur, gold-bearing hydrothermal fluids shape while hot rocks warmness ground water. An instance of those low-sulfur fluids are hot springs like those at Yellowstone country wide Park. The ores of round Mountain, Nevada, are usual low-sulfur deposits.
An ore is a rock that carries sufficient of a metallic or a steel compound to make extracting the steel worthwhile: low-grade ores include a small percent of the metallic or its compound. high-grade ores include a bigger percentage.
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ldentification of a disease resistance locus in arabidopsis that is functionally homologous to the rpg7 locus of soybean
It was identified that a disease resistance locus in Arabidopsis is functionally homologous to the rpg1 locus of soyabean.
How was disease resistant locus identified in Arabidopsis?Using an avirulence gene that was previously cloned from a pathogen that does not affect Arabidopsis, the new disease resistance locus RPS3 in that plant was discovered. Pseudomonas syringae pv. tomato strain that is virulent on Arabidopsis was transformed with the avrB avirulence gene from the soybean pathogen, and conversion to avirulence was tested on Arabidopsis plants. On most Arabidopsis ecotypes, but not all, the avrB gene was avirulence active. Of the 53 ecotypes that were tested, eight were susceptible and 45 were resistant to a P. syringae pv. tomato strain that carried avrB. Crosses between the susceptible ecotype Bla-2 and the resistant ecotype Col-0 were used to study the transmission of this resistance. The ratio of resistant to susceptible F2 plants from this cross was almost 3:1, showing that ecotype Col-0's solitary dominant locus, RPS3, controls resistance to P. syringae that expresses avrB. RPS3 was located on chromosome 3 near markers M583 and G4523 and or = 1 cM from RPM1, another disease resistance locus, using RFLP analysis. The locus RPG1 in soybean regulates resistance to P. syringae strains that possess avrB. As a result, RPG1 and RPS3 both provide resistance to avrB-specific diseases, raising the possibility that these genes are homologs.
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The correct question is Identification of a disease resistance locus in Arabidopsis that is functionally homologous to the RPG1 locus of soybean
Epithelial cells that are adapted for absorption usually have ________ at their free surface.
Answer:
Epithelial cells that are adapted for absorption usually have ___Microvilli_____ at their free surface.
which statement best describes the difference between the sympathetic and parasympathetic nervous systems?
Answer:So the answer that correctly defines these two systems is (A). The sympathetic nervous system prepares the body for strenuous activity and the fight-or-flight response, whereas the parasympathetic nervous system conserves energy and regulates the rest-and-digest state.
Explanation:
The Ribosome is to protein as the Nucleolus is to _______________________. Group of answer choices Lysosome Energy Glucose Ribosome
Answer:
Ribosomes are involved in protein synthesis. Almost all enzymes are proteins. Hence, ribosomes make enzymes too. Chemical structure of hormones is diverse including steroid, eicosanoids, amino acids derivatives, proteins and peptides. Hence, except proteinous hormones, all other types of hormones cannot be synthesized by ribosomes.Ribosomes are not involved in starch manufacture.Was this answer helpful?
What general information about the serengeti do we need to research to further investigate the causes for the changes in the african buffalo population?
Water is what we need to research to further investigate the causes for the changes in the african buffalo population since there is lack of water in serengeti.
Aside from water here are some other factors that are affecting the african buffalo population:
High biodiversity exists.Varying terrainLow predator density relative to prey densityAnimals called buffalo reside in the Serengeti. From 1960 to 1975, the buffalo population significantly grew. Tanzania is the home of the Serengeti. It is a sizable space. The Serengeti is home to a wide variety of species. Photographs are being taken of them by researchers. It has a lot of large plant-eating creatures for its size. There are numerous biodiversities there.
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Which of the following represents arrow B? ( Look at Photo )
A. Carbon Dioxide
B. Glucose
C. Oxygen
D. Blood Vessel (capillary)
if its select all that apply A and C if no its C
Please Help due soon.
Explanation:
marshes and swamps.
answer