Explain why chemogenetic based methods of regulating cellular signaling result in poor temporal control of biochemical pathways relative to optogenetic based methods.

Answers

Answer 1

Answer:

They use different detecting methods to assess neuronal circuits

Explanation:

Chemogenetics is a technique widely used in neuroscience research to explore signaling interactions by means of genetically modified receptors capable of interacting with small molecules. Chemogenetics was first used to determine the function of the chalcone isomerase gene by inducing mutations that altered its substrate specificity. On the other hand, optogenetics is a bioluminescence-driven genetic technique used to control genetically modified neurons that express light-gated ion channel genes. This technique is also used to monitor neuronal networks. In consequence, optogenetic and chemogenetic techniques have recently been combined in order to analyze neuronal circuits, it by analyzing the same actuator molecule.


Related Questions

2 Diseases of a cassava

Answers

The overall outcome of the activities carried out under the CaCESA initiative

will improve cassava production and productivity. The effectiveness of

program is based on five axes:

- provision of healthy cassava cuttings to vulnerable families;

- the organization of extensive awareness and communication campaigns;

- national and regional coordination of actors in the production chain and

cassava post-production;

- the improvement of cultivation, processing and conservation practices

cassava;

- control and management of the spread of diseases, whether they are transmitted

insects and / or infected cassava cuttings.

To achieve these results, it will be necessary to build capacity at different

levels. The objectives will be achieved through the implementation of appropriate activities

Explanation:

Answer:

Explanation:

Oidium manihotis

Root Rot Pathogens

forks over knives movie



1. Do you feel that eliminating all "animal-based foods" is the solution to reverse and prevent the chronic diseases that afflict most Americans and other industrialized nations?

2. Do you feel that government agencies, like the USDA, promote eating an animal-based diet? Why or why not?

3. Given this "sudden epidemic" of obesity in America within the last 30 years, do you feel the main cause of our "growing nation" is due to an animal-based diet, increased consumption of processed foods and refined sugars, or a decline in physical activity?

4. Do you feel the success of the patients was due to a) the increased amount of fruits/vegetables and plants or b) the elimination of meats or c) a combination of both? Why? Use information we've learned in class to justify your answer.

5. What part of the movie really stood out to you (good or bad) and why? Be very specific. This is where you show me you paid attention to the entire documentary.

Answers

Answer:

1. Yes

2. No

3. Yes

Explanation:

Yes, the elimination of the animal based foods decreases and reduce chronic diseases in many developed countries such as US and England etc. but meat is also very necessary for animal diet due to the presence of high protein content.

No, USDA does not promote the intake of an animal-based diet. this agency promote the intake of nutritious food in a limited amount so it does not cause any disease. They recommend the eating of Grains, Fruits, Protein, Foods, Vegetables and Dairy products in a limited amount.

Yes, the main cause of obesity in Americans is due to two reasons, first cause is the intake of meat in large amount and second cause is the decline in physical activity.

The success of the patients was due to combined effect of increased amount of fruits/vegetables and plants and the elimination of meats. By using these two element the patient will quickly recovered.

During an immune response, some cells of the immune system expose antibodies and,
thereby, cause pathogens to be immobilized and form clumps. Which cells of the immune
system have this
function?

A) killer T-Cells
B) helper T-Cells
C) suppressor T-Cells
D) macrophages

Answers

i think the answer is B) helper T-Cells

The diagram shows two charged objects, A and B.
Based on the field lines, what are the charges of the
objects?
3
A: positive
B: negative
O A: negative
B: positive
O A negative
B: negative
OA: positive
B: positive
A
B)
AR
NAL
Save and Fit

Answers

Answer:

A: positive

B: negative

Explanation:

Hope it helps.

Answer

A is positve and B is negitive

Explanation:

For 2 minutes write down every sound you hear. Write in dot points.

What was the quietest noise? What was the loudest noise? Did you have any distractions?

Answers

Answer:

Sounds:

- water dripping

- tv

- ceiling fan

- siblings quarreling

- sparrows chirping

1- The sound of water dripping in the kitchen.

2- the sound of the tv.

3- yes, the Ceiling fan's sound.

Which sentence is punctuated correctly?
O A. Even the concept of beauty may be disputedhrhrhrh people often fail to
see beauty; that is obvious to others.
O B. Beauty may be in the eye of the beholder writers have different
ideas; about what beauty means.
O c. Some believe that, beauty indicates natural goodness others
believe that beauty is merely superficial.
O D. Keats said that truth is beauty: Tolstoy said that the idea that
beauty is good is an illusion.

Answers

Answer:

D. Keats said that truth is beauty: Tolstoy said that the idea that beauty is good is an illusion.

Explanation:

Hope it helps.

What is the behavioral biology, ethology, and comparative psychology?

Answers

Answer:

Comparative psychology and ethology psychology are both about animal science ( that is all i know about behavioral biology, ethology, and comparative psychology )

Herceptin cancer fighting antibodies cannot be produced through genetic engineering of bacteria. What is used instead to accomplish this? A. Selecting cells that produce a large amount of Herceptin to reproduce over generations B. Genetically engineered mammalian cells C. Genetically engineered Bacteriophages D. Producing them with chemicals instead of inside cells

Answers

Answer:

B. Genetically engineered mammalian cells

Explanation:

Herceptin is a monoclonal antibody that binds (attach) to specific antigens in cancer cells to destroy them. This antibody is used in the treatment of different types of cancers including breast and gastric carcinoma, in which HER2/neu protein is overexpressed. Herceptin targets HER2/neu receptors present in cancer cells to kill them. HER2/neu is a protein signaling receptor involved in cell proliferation, thereby this antibody works to selectively target cells that have an excess of HER2/neu receptors such as gastric and breast cancer cells.

Which of the following processes requires energy from the cell?

A.
Osmosis

B.
Active transport

C.
Diffusion

D.
Passive transport

Answers

The following processes requires energy from the cell - B. active transport

Active transport is used by cells to get required molecules such as glucose and amino acids. It requires energy in form of adenosine triphosphate (ATP) is known as primary active transport.

Active Transport works against the concentration gradient and therefore needs energy.Passive transport such as Diffusion and Osmosis, from areas of high concentration to areas of low concentration without the need for energy

Thus, the following processes requires energy from the cell - B. active transport.

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Which statement describes the moment magnitude scale?
O It measures only small earthquakes.
It collects data using a seismograph.
It shows only the strength of seismic waves that were produced.
Olt determines the amount of damage caused by an earthquake.

ans- it collects seismograph

Answers

Answer:

As shown in the edited answer, the correct choice is B

Seismograph is used to record motion of Earth during occurrence of  earthquake. Moment magnitude scale collects data using a seismograph.

What moment magnitude scale?

The moment magnitude scale is referred to total moment release of the earthquake.

Moment is a product of the distance moved and the force required for it to move . It comes from modeling recordings of the earthquake at various stations.

Scientists using the moment magnitude scale to measure the earthquakes size till magnitude 9.5 which is the largest earthquake unit recorded since seismographs were invented.

Thus, the correct option is B.

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Use the following information to answer the question below.

Two true-breeding stocks of pea plants are crossed. One parent has red, axial flowers and the other has white, terminal flowers; all F1 individuals have red, axial flowers. The genes for flower colour and location assort independently.


If 1000 F2 offspring resulted from the cross, approximately how many of them would you expect to have red, terminal flowers?

Answers

Answer:

750

Explanation:

With the f1 generation all being red flowers we can conclude that Red is dominant (R) and white is recessive (r).

This leads to the f1 generation having Rr. If you breed two Rr together you get

1 RR

2 Rr

1 rr

75% of the f2 will have red flowers. So if you take 1000 and multiply it by .75 you will get 750

Approximately 750 flowers will be Red.

(5 points)
The organ responsible for filtering up to 95% of th
maintaining body pH is the
pancreas.
urethra.
kidney.
A pancreas
B urethra
C kidney
D gall bladder

Answers

Answer:

C. Kidney

Explanation:

The kidney is a vital organ in the human body. It is bean shaped and helps in the filtration of toxic substances and wastes from the body fluids which is then reabsorbed into the bloodstream.

The kidney also controls the level of water, pH and sodium levels. It however controls the blood pH by excretion of hydrogen ions and forming bicarbonate which ensures the blood pH is within its optimal and normal range.

Answer:

kidneys

Explanation:

The kidneys are the body's filtration system, and are responsible for filtering out the fluids in the body. The biproduct of this is called urine and is removed from the body

1. What must occur for a double-helix strand of DNA
transcription into RNA? What enzymes or protein
2. What are two key differences between DNA and I
composition and location within the cell.
3. Why does DNA transcribe itself into RNA? What i
cell?
4. How might a mistake during transcription impact t
organism? What is the biological name for such a
5. Provide the corresponding RNA strand that would
segment of DNA: ATTCGCACT

Answers

1) What must occur for a strand of double-helix DNA  before it can transcribe itself into RNA is the DNA must unwind its double- helix near the gene that is going to be transcribed. This region that the DNA has opened up is called transcription bubble.  

2) The two key differences between DNA and RNA is that DNA contains  sugar deoxyribose, while RNA contains sugar ribose. The second key difference is DNA's nitrogen bases are adenine, cytosine, guanine and thymine ( A, C, G, T )  while in RNA instead of thymine there is the uracil base.

( A, C, G, U )

3) The reason DNA transcribes itself into RNA because that is the whole goal of the process called transcription where a strand of DNA is copied into a new molecule of mRNA ( messenger RNA ) to to construct a functional product such as a protein.

4) A error during the process of transcription can change how the organism's  physical characteristics or also can impact the way how DNA codes the phenotype. The name that was given for this situation is called a Mutation.

5)  DN: ATTCGCACT -----------> RNA: AUUCGCACU

( DNA: A, G, C, & T while RNA: A, G , C , & U )

( DNA: A = T, G = C)  (RNA: A = U, G = C)

Below are two chemical equations. One is for cellular respiration and one is for photosynthesis. Correctly place the reactants and products in the right location to complete both equations.
Photosynthesis: H20 +H20------------->C6H12O6 +O2
+solar energy CO2
Cellular Respiration:O2+C6H1206 -------->CO2 + H2O
+02

Answers

Answer:

Photosynthesis: 6CO₂ + 6H₂O + solar energy ----> C₆H₁₂O₆ + 6O₂

Cellular Respiration: C₆H₁₂O₆ + 6O₂ ----> 6CO₂ + 6H₂O + ATP

Hope that helps.

The correct equation for cellular respiration and one for photosynthesis are:

Photosynthesis: 6CO₂ + 6H₂O + solar energy ----> C₆H₁₂O₆ + 6O₂

Cellular Respiration: C₆H₁₂O₆ + 6O₂ ----> 6CO₂ + 6H₂O + ATP

What is cellular respiration?

Cellular respiration is a process of converting food into energy that can be used in many processes. It happens when oxygen is combined with food material and releases carbon dioxide as a waste product.

The correct reaction of photosynthesis is when carbon dioxide and water are combined with sunlight to form glucose and oxygen.

The correct reaction of cellular respiration is when glucose and oxygen react and release carbon dioxide and water and energy,

Thus, the correct reactions are:

Photosynthesis: 6CO₂ + 6H₂O + solar energy ----> C₆H₁₂O₆ + 6O₂

Cellular Respiration: C₆H₁₂O₆ + 6O₂ ----> 6CO₂ + 6H₂O + ATP

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why the swimmer push the water backward​

Answers

to go propele themselves across the water

Answer:

[tex]\boxed{\mathrm{view \: explanation}}[/tex]

Explanation:

Swimmers push water backwards to propel forwards. In other words, swimmers push their hands and legs against water to move forward. This is stated in the third law of motion, for every action, there is an equal and opposite reaction.

percolation in terms of biology

Answers

Answer:

[tex]\boxed{\mathrm{view \: explanation}}[/tex]

Explanation:

Percolation in terms of biology means filtration of a liquid substance through a porous medium.

Desribe the structure of amino acids including what makes amino acids different from each other

Answers

Answer:

1) Amino acid contains a central carbon atom attached to: an anime group, carboxyl group, hydrogen atom and a side chain

2) The side chain of each amino acid differentiates from one another

Please find the description below

Explanation:

Amino acids are monomeric chemical compounds that forms the make up of a protein. Amino acids , like every other chemical compound, have a structure. Amino acids have two functional groups i.e. amine group (-NH2) and carboxylic acid group (-COOH).

All amino acids, which are naturally 20 in number have basic parts in common namely: 1) a central carbon atom, also called the alpha carbon 2) a hydrogen atom 3) an amine group i.e. (-NH2) 4) a carboxyll group i.e. (-COOH)

These are the basic parts of all amino acids, however, the difference between the amino acids is found in the series of different atoms called Side chains or R group that attach to the alpha carbon. These R group makes each amino acid specific and different. For example, a side chain containing sulphur (CH3-S-(CH2)2) is the R group of methionine. Each amino acid has a different side chain attached to the basic structure listed above.

Come up with your own story of a trophic cascade, describing how the organisms occupying the different trophic levels would be affected

Answers

Answer:

The leafhoppers eat plant tissues and, at the same time, they are eaten by spiders that are the food of large lizards. Finally, these lizards are the food of birds that are eaten by snakes.

Explanation:

The food chain starts with primary producers such as plants and algae (i.e., level 1), then goes through herbivorous species including insects and fish (level 2) and finally ends with carnivores such as rodents, snakes and hedgehogs (levels 3, 4 and sometimes 5, which depends on presence of larger predators). Thus, the trophic levels are represented by the number of steps of the food chain. In an ecosystem, the organisms can also be classified according to the mode of obtaining the food in producers (autotrophs), consumers (heterotrophs) and reducers (detritivores).

Which of these is an example of a common?
A. Internet
B. Personal computer
C. Cell phone
D. Video game

Answers

Answer:

I think it is A. Internet

Explanation:

2. What can you conclude from your results about the relative effectiveness of antiseptics vs. disinfectants in preventing the growth of E. coli

Answers

Answer:

Efficacy o disinfectant is relatively greater than that of antiseptics

Explanation:

Most of the reason has to do with the fact that antiseptics are made in a mild form so as to not harm human tissue, while disinfectants are more concentrated and ought to be applied directly to surfaces in order to sanitize them.

Robert Baratheon had dinner at his favorite Italian restaurant. His menu consisted of a salad, a large plate of spaghetti, garlic bread, and wine. For dessert, he consumed “death by chocolate” cake and a cup of coffee. He topped off his evening with a cigarette and brandy. He returned home and, while lying on his couch watching television, he experienced a pain in his chest. He called 911 because he was certain he was having a heart attack. Robert was told his heart was fine, but he needed to watch his diet. What happened to Robert?

Answers

Answer:

he was having a ahstma attack

Explanation:

21. Evidence in support of the importance of endosymbiosis in the evolution of
eukaryotic cells is:
a, Organelles that have their own unique unique DNA and ribosomes
Organelles that have a double membrane
6. Organelles are in the same size range as free living prokaryotes
d. All of the above

Answers

Answer:

d. All of the above

Explanation:

The theory of endosymbiosis is important as it explains the evolution of  eukaryotic cells from prokaryotic cells.

This theory also explains the origin of chloroplast and mitochondria. Several evidences in support of the importance of endosymbiosis in the evolution of  eukaryotic cells are as following:

Organelles have their own separate DNA and ribososme.Organelles that have a double membrane  (inner and outer).Organelles are in the same size range as free-living prokaryotes.

Chloroplast and mitochondria are the examples of such organelles.

Hence, the correct answer is "d".

When curare, a South American arrow poison, is placed on a nerve-muscle preparation, the muscle though a neurotransmitter is still being released from the nerve. Give a possible explanation for the action of curare (be sure to include specific details explaining does not contract when the nerve is stimulated, even how and why).

Answers

Answer:

In a muscle contraction,neurotransmitter acetycholine stimulate the post synaptic membrane of the neuron or the sarcolemma  of the muscles cells at the motor end plate .This neurotransmission effect  leads to the opening of ligand gated sodium channels.

Therefore action potential(Endplate potential) is transmitted across the synaptic juction to to the muscles to  bring  about contraction of muscles(effector) .Therefore Acetycholine is refereed to as excitatory hormone.

Curare works as competitive inhibitor of acetycholine at the motor end plate. It prevents the binding of Acetycholine with the endplate.Therefore, ligand gated Na+channels can not open, thus End potential can not be  generated due to lack of depolarization, thus contraction of muscles is inhibited.

Thus,despite the fact that the neurotransmitter is produced, the curare has blocked the end plate.So, no muscles contraction will occur because ,no place for the the excitatory acetylcholine to bind with.Hence the the muscle cells are in the permanent state of  relaxation (resting membrane potential).

Animals poisoned with this substance usually asphyxiate because of paralysis of the diaphragm, external and internal inter-coastal muscles and  collapse of the lungs and therefore failure of the entire respiration  muscles and system.Thus lack of oxygen from failed breathing.

Explanation:s

In a

Considering the same population of cats as in Part A, what is the expected frequency of each genotype (TLTL, TLTS, TSTS ) based on the equation for Hardy-Weinberg equilibrium? Keep in mind that you just learned in Part A that: The allele frequency of TL is 0.4. The allele frequency of TS is 0.6.

Answers

Answer and Explanation:

Due to some technical problems, you will find the complete answer and explanation in the attached file.

Phytoplankton, shown on the left in the image below, are microscopic organisms that can be found in freshwater and salt water environments. They perform photosynthesis to get energy and act as an important food source for larger organisms, such as the whale that is shown on the right. Phytoplankton A large whale. Which characteristic describes the whale but not its food source, the phytoplankton? The whale is heterotrophic. The whale has cell walls. The whale is unicellular. The whale is a prokaryote.

Answers

Answer:

The whale is heterotrophic.

Explanation:

All living organisms require energy for their life processes. In nature, this energy source is obtained by feeding on one another. When one organism eats another, it gets energy. In this case, a large whale is described to be reliant on a photosynthetic phytoplankton for its energy source.

The phytoplankton is capable of producing its own energy source (food) via the process of photosynthesis. Hence, making it an autotrophic organism. However, since the large whale is dependent on the phytoplankton for food/energy source, it is regarded to be heterotrophic i.e. incapable of producing its own food, hence, depends on other organism like phytoplankton in this case.

Answer:

a

Explanation:

Flicker-fusion is the ability to distinguish many seperate flashes of light simultaneously. How do most flying insects compare to humans and why?

Answers

Answer:

Flicker fusion is the ability to distinguish many separate flashes of light simultaneously.

Flying inscets and humans, both have the ability of flicker fusion and it provides them to give a better visual of a fast-moving objects. Though humans have less flicker fusion threshold than insects.

They both can change their flicker fusion threshold as a function of viewing stimulus size, distance, luminance, intensity, achromatic vs. chromatic, and retinal location.

What type of transport occurs in the cell membrane when a person does sports and is consuming alcohol?

Answers

Cellular transport: it is the exchange of substances through the plasma membrane, which is a semipermeable membrane. Transport routes are through the cell membrane

It allows the metabolism waste to be expelled from its interior It allows the movement of substances that it synthesizes as hormones. Metabolic energy: is the way in which it acquires nutrients through processes of incorporation into the cell of nutrients dissolved in water.

Therefore, when the person consumes alcohol in excess the ce transport is part of the disincorporation of toxic waste, while when the person does sports, and is supposed to have a balanced diet, the cellular transport uses it for his metabolic energy.

Sean and Tommy are debating the positive and negative impacts of technology on environmental quality. Sean is listing the positive impacts. Which of the following would help his argument? (2 points) Select one: a. Factories add to water and air pollution b. Technology can disrupt natural processes c. Technology has helped make recycling to be more efficient d. More people buy smart phones and tablets ITs listing POSITIVES not negatives, so it has to be C, right?

Answers

It will be b I’m pretty sure

If any of these shark species were to go extinct, what would most likely be a result to their ecosystems?
Select one:
a. Nothing, sharks are only human killers.
b. The ecosystem would collapse because sharks are vital to their ecosystems.
c. The habitat would develop new species. With the sharks gone, new organisms can move in to fill that niche.
d. The ecosystem would get healthier. Sharks spend the majority of their time hunting and searching for humans to kill in there habitat​

Answers

Answer:B

Explanation:

They are vital to there ecosystem

The movement of ions and other atomic or molecular substances across cell membranes without the need for energy input is known as

Answers

Answer:

passive transport

Explanation:

The movement of ions across a cellular membrane without the need for energy input is known as passive transport. Diffusion is the passive movement of molecules from an area of high concentration to low concentration. Voltage describes the difference in electrical potential between two separate points, and isotonic movement describes the activity of a system at equilibrium.

Answer:

Passive transport

Explanation:

The movement of ions across a cellular membrane without the need for energy input is known as passive transport. Diffusion is the passive movement of molecules from an area of high concentration to low concentration. Voltage describes the difference in electrical potential between two separate points, and isotonic movement describes the activity of a system at equilibrium.

PENN

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What will be the pressure exerted by the object if 5000N of the force is acting on an area of 200 cm square At a central train station, there are 4 different train routes with trains that leave every 6 minutes, 10 minutes, 12 minutes, and 15 minutes. If each train can hold up to 200 passengers, what is the maximum number of passengers who can leave the station on a train in one hour? Find the value of f(-1)g(-1) In which parking situations should you use your parking brake?A. only when you're parking on a hillB. only when you're parking on flat groundC. alwaysD. only when you're parked facing uphill The double number line shows that Faye can sort 150 recyclable items in 3 minutes. Based on the ratio shown in the double number line, how many recyclable items can Faye sort in 4 minutes? items Following are the transactions of a new company called Pose-for-Pics. Aug. 1 Madison Harris, the owner, invested $12,000 cash and $51,600 of photography equipment in the company in exchange for common stock. 2 The company paid $2,300 cash for an insurance policy covering the next 24 months. 5 The company purchased office supplies for $2,280 cash. 20 The company received $3,250 cash in photography fees earned. 31 The company paid $870 cash for August utilities. Prepare general journal entries for the above transactions. if a/b and c/d are rational expressions then a/b divided by c/d =a times d/b times c true or false the angle of elevation of the top of a tree from a point 27m away on the same horizontal ground as the foot on the tree is 30 degrees .find the height of the tree. PLEASE ANSWER QUICKLY: Two boxes have the same volume. One box has a base that is 5cm by 5cm. The other box has a base of 10cm by 10cm. How many times as tall is the box with the smaller base than the larger base? Dr. Chen studies how people grow and change during late adolescence and young adulthood. Dr. Doherty focuses on several traits that distinguish one person from another. Dr. Chen is a(n) _____ psychologist; Dr. Doherty is a _____. Use the Product Rule of Logarithms to write an expression equivalent to In(6a+ 9b). Make sure to use parenthesis around your logarithm functions In(x +y) name the important valley of nepal Even though land was cheap in the frontier, why did farmers have trouble turning a profit?A. Taxes on the land were very highB. People did not want the type of crops grown in the WestC. The land was infertile and could not grow many cropsD. Farm equipment was still very expensive to buy and maintain Martin has severe myopia, with a far point on only 17 cm. He wants to get glasses that he'll wear while using his computer whose screen is 65 cm away. What refractive power will these glasses require? Harpeth Valley Water District has a bond outstanding with a coupon rate of 3.63 percent and semiannual payments. The bond matures in 23 years, with a yield to maturity of 4.17 percent, and a par value of $5,000. What is the market price of the bond 7.Why are we able to drink cold drink with straw from a bottle? in the diagram AB =AD and The esophagus, a tube that carries food to the stomach, is constantly being scraped as food travels through it. Why does the esophagus not deteriorate through a persons lifetime? Cells can anabolize the food prior to entering the esophagus. Cells are constantly dividing and replacing old or damaged cells. Cells promote a fluid to build up along the esophagus to reduce friction. Cells build a type of protein called enzymes that act as an armor. A car can go from rest to 90 kmh in 10 s. What is its acceleration? which religious group may refuse autopsy?