Death receptors (SDRs) result in apoptosis however additionally stimulate proinflammatory "non-apoptotic" signaling (e.g. NF-κB and mitogen-activated protein kinase (MAPK) activation) and inhibit awesome steps of DR-activated maturation of procaspase-8. To take a look at whether or not isoforms of cellular FLIP (cFLIP) or its cleavage products differentially regulate DR signaling, we mounted HaCaT cells expressing cFLIP(S), cFLIP(L), or mutants of cFLIP(L) (cFLIP(D376N) and cFLIP(p43)). cFLIP editions blocked TRAIL- and CD95L-induced apoptosis, but the cleavage pattern of caspase-8 in the dying inducing signaling complicated was different: cFLIP(L) brought on the processing of caspase-8 to the p43/41 fragments irrespective of cFLIP cleavage. cFLIP(S) or cFLIP(p43) blocked procaspase-8 cleavage. Analyzing non-apoptotic signaling pathways, we found that TRAIL and CD95L activate JNK and p38 within 15 min. cFLIP variations and exclusive caspase inhibitors blocked late demise ligand-induced JNK or p38 MAPK activation suggesting that these responses are secondary to mobile death. cFLIP isoforms/mutants also blocked dying ligand-mediated gene induction of CXCL-8 (IL-8). Knockdown of caspase-8 completely suppressed apoptotic and non-apoptotic signaling. Knockdown of cFLIP isoforms in most important human keratinocytes improved CD95L- and TRAIL-induced NF-κB activation, and JNK and p38 activation, underscoring the regulatory position of cFLIP for these DR-mediated signals. Whereas the presence of caspase-8 is fundamental for apoptotic and non-apoptotic signaling, cFLIP isoforms are strong inhibitors of TRAIL- and CD95L-induced apoptosis, NF-κB activation, and the late JNK and p38 MAPK activation. cFLIP-mediated inhibition of CD95 and TRAIL DR could be of necessary importance for the duration of keratinocyte skin carcinogenesis and the activation of innate and/or adaptive immune responses induced using DR activation in the skin.
Any of two or greater functionally comparable proteins that have a similar but not same amino acid sequence and are either encoded by means of extraordinary genes or with the aid of RNA transcripts from the identical gene which have had special exons removed.
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I need help with these questions about impulse and momentum for my test review!
Help will be appreciated :)
A town is considering new sources of electricity. Which of the following sources of electricity would be the MOST environmentally safe choice?
A
hydroelectric dam
B
solar power station
C
coal-fired power plant
D
natural gas power plant
Group of answer choices
A
Answer:
B
Explanation:
Answer:
B
Explanation:
Multiple Choice: Write the letter of the correct answer.
1. uses neurons to send and deliver messages that are fast acting, localized, and short-lived.
a. Endocrine System
b. Nervous System
c.Circulatory System
2. sends slower-moving hormones through the blood that target broad areas and have more lingering effects.
a. Endocrine System
b. Nervous System
c. Circulatory System
3. cook up hormones and secrete them into the blood without using ducts.
a. Endocrine gland
b. Nervous gland
c.Circulatory gland
4. A is a just any structure that makes and secretes a hormone.
a. organ
b. gland
c. cell
5. is the master gland of the body.
a. Endocrine gland
b. Pituitary gland
c. Thyroid gland
Answer:
1 b i
2 c
3 a
4 b
5 I don't know
i think this is the answer
What type of cells reproduce by mitosis (scientific and basic word)? List three examples.
What type of cells reproduce by meiosis (scientific and basic word)? List examples.
Below, list the steps of mitosis in order then give a brief description of what happens during each step:
Below, list the steps of meiosis in order then give a brief description of what happens during each step:
Will give brainiest answer fasttttttttttt plz and no oneanswer just cause of points
Explanation:
1. Multi celled organisms, body(somatic) cells, single celled organisms.
2. gametes (Sex cells), haploid cells.
3. Interphase - when they are not dividing.
Prophase - nuclear membrane breakdown, chromatin turn to chromosomes and spindle fibers appears.
Metaphase - nuclear membrane completely gone, chromosomes line up along the middle and spindle fibers joins pole to centromere.
Prophase - spindle fibers contract and double stranded chromosomes pulled apart to either poles.
Telophase - nuclear membrane forms, two cells separate, spindle fibers breakdown and chromosomes lengthen and turn to chromatin.
4. I'm not sure about this one.
1. Multi celled organisms, body(somatic) cells, single celled organisms.
2. gametes (Sex cells), haploid cells.
3. Interphase - when they are not dividing.
What are multi celled organisms?A multicellular organism is an organism that consists of more than one cell, in contrast to unicellular organism.
Multicellular organisms are those composed by multiple cells. They are classified in 13 major groups of terrestrial living beings, including animals, plants, fungi, ciliates, algae, and foraminifera. The number of cells per organism range from some tens to up to several million.
Animals, plants, and fungi are multicellular organisms. Multicellular organisms are much bigger in size and are very complex and intricate in their composition along with structure. Human beings, animals, plants, insects are examples of multicellular organisms.
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How does gravity relate to a streams ability to erode and deposit materials
Which statement correctly describes part of the carbon cycle?
o A. The amount of carbon in the soil increases when plants decay.
OB. The amount of carbon in the ocean decreases when fossil fuels are burned.
o C. The amount of carbon in the atmosphere decreases when igneous rocks form.
o D. The amount of carbon in the atmosphere increases when photosynthesis occurs.
Answer:
A is the right answer
Explanation:
A is the right answer
WILL GIVE BRAINLIEST!!!!!!
Which characteristic is shared by both prokaryotes and eukaryotes?
need oxygen gas to breathe
make their own food
contain genetic material
have organ systems
Answer:
Contain gentic material
both have DNA
Explanation:
Prokaroytes dont have organ systems
and the rest are incorrect
What is the process by which populations of organisms change over time?
Answer:Evolution is the process by which populations of organisms change over generations. Genetic variations underlie these changes
Explanation:
In a certain species of plant, the color purple (P) is dominant to the color white (p). According to the Punnett Square, what is the probability of an offspring being purple?
Answer:
If both are (PP and ww) and one is dominant the other is recessive then it is 100% purple.
IF both are heterozygous (pw) then it is 75% purple and 25% white
if one is Hetro(pw) and the other is (ww) 50% white 50% purple
Explanation:
Question 24 (5 points)
Mitosis is the cell cycle that creates 2 identical cells. Body cells like skin cells and bone cells are created by this cycle,
True
O False
Answer:
;f,;lg,lfm,pf
Explanation:
Answer:
false
Explanation:
Mitosis is used to produce daughter cells that are genetically identical to the parent cells. The cell copies - or 'replicates' - its chromosomes, and then splits the copied chromosomes equally to make sure that each daughter cell has a full set
What would happen to a plant if the chloroplasts in its cells became damaged?
(1 point)
O The plant would be unable to make protein.
O The plant would be unable to reproduce.
O The plant would not have a rigid structure.
O The plant would not make glucose and oxygen.
If the chloroplasts of the plant cell become damaged, it would not be able to make glucose and oxygen. So the correct option is D.
What are chloroplasts?Photosynthesis, the mechanism by which light energy is transformed to chemical energy and results in the generation of oxygenation and energy-rich organic molecules, takes place in the chloroplast, a structure found inside the cells of green algae and plants.
Endosymbiotic hypothesis holds that mitochondria and chloroplasts, which are energy-producing structures in eukaryotic cells, are descended from photosynthetic cyanobacteria, which are free-living near cousins of chloroplasts.
A plastid is a sort of body that is formed like a disc, an oval, or a circle and is used to synthesise and store food. Chloroplasts are one type of plastid. The green colour of chloroplasts, which derives from the existence of two pigments called chlorophyll a and chlorophyll b, sets them apart from other plastid types.
These pigments have the capacity to absorb light energy for the purpose of photosynthesis. Carotenoids are one of the additional pigments found in chloroplasts that act as accessory pigments, capturing sun energy and transferring it to chlorophyll.
Therefore the correct option is D.
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Answer:
Yes the first answer is correct it is d
Explanation:
Which structure in plants allowed the first land plants to survive out of water?
A. cuticle
B. epidermis
C. guard cell
D. spongy mesophyll
Answer:
A
Explanation:
The structure of plants that allowed the first land plants to survive out of water is known as the cuticle. Thus, the correct option for this question is A.
What were the first plants to live on land?The first plants that were tends to live on land are the Non-vascular plants, which include mosses and liverworts, which were the first-ever land plants. They do not have much of an internal support system but have slightly simpler material for the same tasks.
Early in their history, land plants also evolved a cuticle. The cuticle is the structure that involves a waxy layer on the outer surface of the aerial parts of a plant that helps to prevent water loss. Sometimes cuticle with details of epidermal cell structure is preserved in fossil plants.
Guard cells play an important role in the opening and closing of the stomata. While epidermis is the outer cell which prevent the whole plant form injury.
Therefore, the structure of plants that allowed the first land plants to survive out of water is known as the cuticle. Thus, the correct option for this question is A.
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Which base sequence is the complementary DNA for GCATAC?
A. CATACG
B.CGTATG
C. GCATAC
D.GTATGC
the largest mass of living material on earth comes from the largest mass of living material on earth comes from microorganisms. plants and animals together. plants. animals
The correct option is A: Microorganisms
The largest mass of living material on earth comes from microorganisms.
Microorganisms are tiny microscopic organisms that can not be seen through a bare eye.
In order to see them, we need a high-resolution microscope.
Fungi, bacteria, protozoa, and algae are microscopic organisms that are found both in marine and freshwater.
All these organisms are single-celled and occur in the form of colonies.
The first microbes are expected to be present on planet 'earth' since early times and were discovered back in the 6th century in India.
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Chymotrypsin is a digestive enzyme that breaks down proteins in the small intestine. A student runs a computer simulation of chymotrypsin
enzyme activity at various pH levels and creates the graph.
Enzyme Activity
10
12
8
pH
According to the graph, at what pH is chymotrypsin the most effective?
04
6
8
O 10
Answer:
C.8
Explanation:
An organelle found in most eukaryotic cells described as "cellular power plant"
Answer:
[tex]\boxed {\boxed {\sf Mitochondria}}[/tex]
Explanation:
The mitochondria is commonly called the powerhouse of the cell.
This is because it is the organelle that makes energy for the cell. The process of cellular respiration occurs in the mitochondria.
Cellular respiration turns glucose from food and oxygen into carbon dioxide, water, and ATP. ATP is useable energy for the cell, its metabolism, and its processes.
Mitochondria are found in eukaryotic cells, because it is a membrane bound organelle.
So, the organelle this question describes is the mitochondria.
Four random genetic matches then formed the following diploid offspring. Using the text box or pen tools, label the alleles on each offspring.
Crossing-over events occur during the prophase 1. After anaphase 2, telophase 2, and citokynesis, 4 gametes are formed. Each gamete has different genetic information. Alleles are labeled in the attached file.
--------------------
Since I do not have the parentals genotype, I will consider two traits, each coded by a single diallelic gene.
Gene 1:
A is the dominant allelea is the recessive alleleLocated in the superior arm of the chromosomeGene 2:
B is the dominant alleleb is the recessive alleleLocated in the inferior arm of the chromosomeI will assume that both parents are heter0zyg0us for both traits, so their genotypes are AaBb.
During gamete formation, the pairs of h0m0logous chromosomes separate after crossing over. Then, sister chromatids also separate. The result is the formation of four gametes.
Each gamete has different information from the combination of h0m0logous chromosomes belonging to the father and to the mother.
Mother
During the prophase of meiosis 1, the mother's homologous chromosomes express two crossing-over events. One of them in the superior arm and the other one in the inferior arm.
The segments interchange between chromosomes involves Gene 1 and Gene 2.
During anaphase 2, sister chromatids separate, and after telophase and cytokinesis, four haploid gametes are formed carrying the following chromosomes,
AB → Parentalab → RecombinantAB → Recombinantab → ParentalFather
During the prophase of meiosis 1, the father's homologous chromosomes express one crossing-over event in the inferior arm.
The segments interchange between chromosomes involves Gene 2.
During anaphase 2, sister chromatids separate, and after telophase and cytokinesis, four haploid gametes are formed carrying the following chromosomes,
AB → ParentalAb → RecombinantaB → Recombinantab → ParentalGametes' destiny is to randomly merge in the process of fecundation, during which a new diploid cell called zygote emerges through fertilization.
The zygote is a complete cell that suffers successive mitosis to form the new organism.
In the exposed example,
Offspring 1 → Parental gamete ab from the mother merged recombinant
gamete aB from the father → genotype aaBb
Offspring 2 → Parental gamete AB from the mother merged recombinant
gamete aB from the father → genotype AaBB
Offspring 3 → Recombinant gamete ab from the mother merged
recombinant gamete Ab from the father → genotype Aabb
Offspring 4 → Parental gamete ab from the mother merged recombinant
gamete ab from the father → genotype aabb
For a better understanding, you can see the image in the attached files in which alleles are labeled.
------
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What is true about the ribosomes found in prokaryotes?
A. Prokaryotic ribosomes are often found attached to the endoplasmic reticulum.
B. Prokaryotic ribosomes are smaller than eukaryotic ribosomes.
C. Prokaryotic ribosomes consist of only a large subunit.
D. Prokaryotic ribosomes are larger than eukaryotic ribosomes.
What is the answer for this?!!!
Answer:
Your answer is B).
Explanation:
If the pH is somewhere around 6.0 when the seeds have been placed, then the flowers will be pink, even if later on you try to change to pH levels of the soil, there will be very little change in the color of the flowers.
Which of the following BEST represents the meaning of empathy?
Group of answer choices
Standing in another person’s shoes
Feeling sorry for another person’s misfortune
Looking through a window at another person
Imitating another person’s actions
Answer:
I would go for A or B
Explanation:
Cause they are the best answers
I hope you do great and have a nice day :D
Answer:
what is the answer. sorry lol im taking the test rn
Explanation:
What can stop climate change and restore the balance of CO2?
Answer:
Power your home with renewable energy. AND . Reducing the use of coal, oil and natural gas is clearly important, but it's not the only way to bring the carbon cycle into better balance
Explanation:
Another option is to speed up the rate at which CO2 is removed from the atmosphere and then sequester the resulting carbon, thereby balancing out the CO2 from fuel combustion.
please help.
Embryonic stem cells are pluripotent because they can
grow into similar types of cells such as blood cells to blood cells.
grow into any type of body cell.
grow into any type of body cell, but they cannot become totipotent.
Answer:
They can grow into any type of body cell.
Explanation:
Stem cells are immature cell types- they are somatic cells, that contain the entire genome of an organism. The genome is made up of DNA, which encodes instructions for the cell.
These may potentially become various other types of cells through the process of differentiation and reach maturity. In differentiation, chemical signalling, and gene expression ultimately determine the cell's fate.
name 1-2 carbohydrates that are not used primarily for energy.
What allows carbon to bond with up to four other atoms at a time and form the macromolecules that are essential to life ?
Answer:
A covalent bond is formed when atoms share electrons in their valence shells. Carbon …
Explanation:
A covalent bond is formed when atoms share electrons in their valence shells. Carbon …
DUE IN ONE HOUR PLEASE HELP
Question 2
A seed germinates when it is buried in nutrient rich soil and watered.
True
Fase
Please ASAP hehehehe i
What will most likely happen if a person does not consume the minimum daily requirement of carbohydrates?
Answer:
the body will break down chitin from the bones and glycogen from the liver hope it helps pls mark brainliest
where is most of the mass of the atmosphere contained?
stratosphere
mesosphere
thermosphere
or troposphere
Answer:
troposphere
Explanation:
Answer: Troposphere
Explanation:
The majority of the mass of the entire atmosphere is contained in the troposphere—between approximately 75 and 80 percent.
A relatively straight river, consisting of small bends, is flowing through an area that is untouched by humans. What will happen to this river over a long period of time?
all you need is in the photo
Answer:
I Belive its the 3 one
Explanation: