ca2 -calmodulin-dependent facilitation and ca2 inactivation of ca2 release-activated ca2 channels

Answers

Answer 1

This article aims to find that [tex]Ca^{2+}[/tex] occupancy of a site on the extracellular side of the CRAC channel ordinarily potentiates its [tex]Ca^{2+}[/tex] as well as [tex]Na^{+}[/tex] currents, and [tex]Ca^{2+}[/tex] dissociation from this site is responsible for the inactivation of its [tex]Na^{+}[/tex] current.

The most extensively studied of the store-operated ion channels, which are widely expressed and crucial to many vital biological processes, is the [tex]Ca^{2+}[/tex]  release-activated [tex]Ca^{2+}[/tex] (CRAC) channel. But little is known about the CRAC channel's molecular makeup or how intracellular or extracellular messengers control it.

It becomes more permeable to monovalent cations with a higher current when extracellular divalent cations are absent, however this monovalent cation current quickly deactivates due to an unidentified mechanism.

Here, it was found that [tex]Ca^{2+}[/tex] occupancy of a site on the extracellular side of the CRAC channel ordinarily potentiates both its [tex]Ca^{2+}[/tex] and [tex]Na^{+}[/tex] currents. [tex]Ca^{2+}[/tex] dissociation from this site, however, results in the inactivation of the channel's [tex]Na^{+}[/tex] current. This [tex]Ca^{2+}[/tex]-dependent potentiation is required for the normal functioning of CRAC channels.

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Related Questions

A 36.0 g sample of metal was heated from 0°C to 55.0°C. It absorbed 150 J of
energy as heat. What is the specific heat of this piece of metal?
Motino
abiD

Answers

A 36.0 g sample of metal was heated from 0°C to 55.0°C. It absorbed 150 J of energy as heat then the specific heat of this piece of metal is 0.0758 J/g.°C  .

The term "specific heat" refers to the amount of energy needed to raise a substance's unit mass by one degree Celsius. This can be mathematically stated as:

q = m×c×ΔT,

where ,

q = the amount of heat

m = the mass of the substance

c = the respective substance's specific heat;

ΔT = the change in temperature.

So, if we want to determine the units for specific heat, we'll just isolate the term in the above formula to get

c = q / m × ΔT                    ( i )

Since heat is measured in Joules ( J ) , mass in grams ( g ) , and temperature in degree Celsius , we can determine that specific heat capacity from equation ( i )  by putting all the given data in this equation ,

c =  150 J / 36.0 g × 55.0 °C = 150 J / 1980 g.°C = 0.0758 J/g.°C

Therefore, specific heat is measured in Joules per g times degree Celsius.

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According to Periodic Law, elements arranged in order of increasing atomic number are placed together in groups having

Answers

Answer: same valence shell configuration and properties

Explanation:

All the following are compounds except. A.water. B.sugar solution. C.aqueous. D.sulphur dioxide

Answers

Answer:

B.sugar solution

Explanation:

A sugar solution is not a compound.

Rather, the solution is a mixture and an impure substance.

A compound is composed of two or more kinds of atoms or elements joined in a definite grouping .The properties of the compound is distinct from those of the individual atoms that makes them. Sugar solution is sugar and waterIt is made up of two compounds not chemically combined.

Calculate the moles of 336 L of carbon dioxide gas (CO2) at STP.

Answers

Answer:

14.99 mols of CO2

Explanation:

STP= 273 k , 1 atm , .0821 gas constant

N=PV/RT

N= 1x336/.0821x273

14.99 mols of CO2

659.6 grams of CO2

PLEASE HELP
Which concept accounts for the whole-number subscripts in chemical formulas?


A. law of multiple proportions


B. Avogadro's law


C. conservation of energy


D. conservation of matter

Answers

Answer:

Law of multiple proportions

Explanation:

which graph above best represents the relationship between the volume and the pressure of a gas?​

Answers

The graph (A) best represents the relationship between the volume and the pressure of a gas.

What is pressure?

The force was applied perpendicular to an object's surface per unit area across which that force is spread is known as pressure. The relationship between pressure and volume can be understand with the aid of ideal gas law.

PV=nRT.

where, P is pressure, V is volume.

It can be seen that when temperature will kept constant then pressure will be inversely proportional to the volume. It can be shown as:

P ∝ 1/V.

Therefore, graph A represent relationship between pressure (P) and volume (V).

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Which is the Lewis dot structure for H3PO4?

Answers

Answer:A

Explanation:

which of these characteristics of all animal cells ? check all that apply
they contain a nucleus .
they are eukaryotic.
they lack member-bond organelles.
they lack in nucleus.
they are prokaryotic.
they contain member-bond organelles.

Answers

Answer:

They contain member-bond organelles.

Explanation:

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Hypertonic, Isotonic, or Hypotonic

cell biology

Answers

Statements 6,9,13,14 are hypertonic, 8,10,12 hypotonic, and 7,11,15 are isotonic solutions.

6. Hypertonic

7. Isotonic

8. Hypotonic

9. Hypertonic

10. Hypotonic

11. Isotonic

12. Hypotonic

13. Hypertonic

14. Hypertonic

15. Isotonic

A hypertonic answer is any external solution that has excessive solute awareness and coffee water concentration as compared to frame fluids. In a hypertonic answer, the internet movement of water will be out of the frame and into the solution.

A hypotonic answer has a decreased awareness of solutes than some other answer. In biology, a solution outdoor of a cell is referred to as hypotonic if it has a decreased attention of solutes relative to the cytosol. because of osmotic stress, water diffuses into the cell, and the cell often appears turgid, or bloated.

A solution that has the same salt concentration as cells and blood. Isotonic answers are typically used as intravenously infused fluids in hospitalized sufferers. Isotonic solutions include electrolyte stability just like plasma in the bloodstream. whilst an isotonic solution is administered, the fluid extent of the affected person is elevated without a fluid shift. not unusual examples of isotonic solutions are zero.nine% ordinary saline and lactated ringers.

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Substances that dissolve in water nd give up OH-ions are considered what

Answers

Your answer would be an Arrhenius base

Hope this helps

1.
A sample of helium gas is heated from 20.0°C to 40.0°C. This heating
process causes the gas to exland to a volume of 585 mL. What was
the original volume of the helium gas?

Answers

Answer:

V₂ = 530.5 mL

Explanation:

Given data:

Initial temperature = 20.0°C

Final temperature = 40.0 °C

Final volume = 585 mL

Initial volume = ?

Solution:

Initial temperature = 20.0°C (20+273 = 293 K)

Final temperature = 40.0 °C (40+273 = 323 K)

Solution:

The given problem will be solve through the Charles Law.

According to this law, The volume of given amount of a gas is directly proportional to its temperature at constant number of moles and pressure.

Mathematical expression:

V₁/T₁ = V₂/T₂

V₁ = Initial volume

T₁ = Initial temperature

V₂ = Final volume  

T₂ = Final temperature

Now we will put the values in formula.

V₁/T₁ = V₂/T₂

V₁ = V₂T₁ /T₂  

V₂ = 585 mL × 293 K / 323 K

V₂ = 171405 mL.K / 323 K

V₂ = 530.5 mL

GIVING BRAINLIEST :D
If water is added to 100. mL of a 0.150 M NaOH solution until the final volume is 150. mL, what will the molarity of the diluted solution be?

Answers

Answer:

0.1 M molar NaaOH

Explanation:

M1V1= M2V2

M1 = 0.150M NaOH

V1=100 ml

V2=150 ml

M2=?

M2= M1V1/V2

M2= 0.150*100/150=0.1 M

Please help!!! Thank youuu I’ll give brainlist to first to get them right

Answers

questions 3 gravity

question 1 meteorites

question 2 orbit

question 4 rocket and gaseous

Answer:

1. moons 2. orbits 3. gravity 4. rocky, gaseous

Explanation:

an atom has 24 protons and 23 electrons and 28 neutrons what charge does this atom have?

-4
+4
-1
+1

Answers

Answer:

1+

Explanation:

the number of protons tells you which element it is in the periodic table, you can notice that there is 1 less electron that then there is protons which means that the element had to give 1 electron away. When you get rid of 1 e- you have 1 proton more that electrons so that's why it's 1+

also the element is Cr

what are the type of mixture in calloid, suspension and solution

Answers

Homogeneous and heterogeneous mixture in colloid, suspension and solution

A colloid is a heterogeneous mixture in which the dispersed particles are intermediate in size between those of a solution and a suspension and within the categories of homogeneous and heterogeneous mixtures there are more specific types of mixtures including solutions is alloys, suspensions, and colloids and a solution is a mixture where one of the substances dissolves in the other and the substance that dissolves is called the solute

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An element with a high ionization energy would most likely be what type of element?
A.
metal with a high electronegativity
O
B.
non-metal with a low electronegativity
o
C.
non-metal with a high electronegativity
O
D.
metal with a low electronegativity

Answers

Answer:

C

Explanation:

It is most likely non metal with a high electronegativity.

There are two opposing processes that occur in a solution in contact with undissolved solute. These are dissolving and ________.

Answers

Answer:

Two process that occur are dissolving and solvent

somebody please help me!!

Answers

Answer:

The given isotope is Br 80

If 35 protons present then its atomic number is 35

Mass number is 80 so its meutrons are 45 because proton+ neutron = mass number

Its electron are 36 because of negative one charge

Explanation:

A meterorite has velocity of 1544 m/s and a mass of 45 kg. Find its momentum

Answers

Answer:

69,480 kg.m/s

Explanation:

The momentum of an object can be found by using the formula

momentum = mass × velocity

From the question we have

momentum = 45 × 1544

We have the final answer as

69,480 kg.m/s

Hope this helps you

Answer:

69,480 kg. m/s

have a nice day!

what are the type of reactions in activation energy?

Answers

Answer:

n chemistry and physics, activation energy is the energy that must be provided to compounds to result in a chemical reaction.The activation energy (Eₐ) of a reaction is measured in joules per mole (J/mol), kilojoules per mole (kJ/mol) or kilocalories per mole (kcal/mol). Activation energy can be thought of as the magnitude of the potential barrier (sometimes called the energy barrier) separating minima of the potential energy surface pertaining to the initial and final thermodynamic state. For a chemical reaction to proceed at a reasonable rate, the temperature of the system should be high enough such that there exists an appreciable number of molecules with translational energy equal to or greater than the activation energy. The term Activation Energy was introduced in 1889 by the Swedish scientist Svante Arrhenius.

Explanation:

Answer:

The activation energy for the forward reaction is the amount of free energy that must be added to go from the energy level of the reactants to the energy level of the transition state. The source of activation energy is typically heat, with reactant molecules absorbing thermal energy from their surroundings.

Explanation:

solid zinc reacts with oxide to form zinc oxide

Answers

Answer:

2Zn(s) + O2(g)------2Zno

Which of the following is a way that human modification of limiting factors causes unbalance in ecosystems.​

Answers

Answer:

D. all of the above

Explanation:

edg 2021

A way that human modification of limiting factors causes unbalances in ecosystems. are habitat loss, pollution, and climate change. Option D. This is further explained below.

What is an ecosystem.?

Generally, An ecosystem is a geographical region in which plants, animals, and other species, as well as weather and topography, coexist to produce a circle.

In conclusion, habitat loss, pollution, and climate change are all human modification of limiting factors causes unbalance in ecosystems.​

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CQ

which of the following is a way that human modification of limiting factors causes unbalance in ecosystems? a. habitat loss b. pollution c. climate changes d. all of the above

calculates the equivalent mass of calcium chlorate CA (CI03) 2

Answers

Answer:

207g

Explanation:

Given compound:

            Ca(ClO₃)₂

The equivalent mass can be derived by summing the molar masses of each atom

  Molar mass of Ca = 40

                            Cl  = 35.5

                            O  = 16

Now solve;

 Molar mass  = 40 + 2(35.5 + 3(16)) = 207g

What should be done in order to increase the gravitational force between two objects?

Answers

Answer:

Decrease the distance between them or increase the mass.

Explanation:

F= GM1M2/ R²

Answer:

decrease the distance between the objects

Explanation:

i did the test and got da epic 100 score

Explain the role of photosynthesis in the cycling of matter between the plant and the person?

Answers

The process of photosynthesis converts light energy into stored chemical energy by converting carbon dioxide plus water into sugars plus released oxygen.

What is photosynthesis ?

Utilizing a process called photosynthesis, plants and other living things may transform light energy into chemical energy that can then be released through cellular respiration to power their activities. Photosynthesis, from the Greek phs (light) and synthesis (putting together), derives from the fact that some of this chemical energy is stored in carbohydrate molecules, such as sugars and starches, which are created from carbon dioxide and water.

Photoautotrophic organisms, such as the majority of plants, algae, and cyanobacteria, carry out photosynthesis. The majority of the energy required for life on Earth is produced and maintained through photosynthesis, which is also primarily responsible for producing and maintaining the oxygen concentration of the Earth's atmosphere.

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Which of these discoveries contradict components of Dalton’s atomic theory?

Answers

Dalton's atomic theory was proposed by John Dalton in 1803. It states that elements are made up of indivisible atoms, atoms of the same element are identical, and atoms cannot be created or destroyed.

What is Dalton's atomic theory?

Dalton proposed that the concept of atoms might be used to explain the laws of definite proportions and the conservation of mass. In his theory, atoms—which he described as "solid, massy, hard, impenetrable, moving particle(s),"—are the minuscule, indivisible units that make up all matter.

It is significant to highlight that Dalton had no knowledge of the potential existence of interior structure in atoms because he lacked the tools necessary to observe or perform further experiments on individual atoms. In a molecular modeling kit, where the various components are represented by spheres of various sizes and hues, we may imagine Dalton's atom as a component. We now know that atoms are not solid spheres, despite the fact that this paradigm is useful in some situations.

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What does oxygen to do to iron

Answers

Iron rusts when it combines with oxygen in the air. Iron rusting is an example of a chemical reaction. In a chemical reaction, substances change into entirely different substances. For example, the iron in the bike and the oxygen in the air have changed into rust.

Identify arrows pointing to bonding electrons.

Answers

Answers:

Identify arrows pointing to bonding electrons.

✔ a, b, d

Identify arrows pointing to nonbonding electrons.

✔ c

Identify arrows pointing to structures containing sigma bonds.

✔ a, b, d

Identify arrows pointing to structures containing pi bonds.

✔ a

Explanation:

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Your question is incomplete. Please check below the full content

Identify arrows pointing to bonding electrons

a)✔a, b, d

b)✔ c

c)✔ a, c, b

d)✔ a

Identify arrows pointing to bonding electrons.

✔ a, b, d

Which type of bond is indicated by an arrow?

The coordinate covalent bond is shown by an arrow with its head pointing towards the direction of the donation of an electron pair, as shown in Figure 2.

What are 5 examples of covalent bonds?

Here are 5 examples of covalent compounds

1 Hydrogen (H2) Hydrogen (H) is the simplest of all elements.

2 Oxygen (O2).

3 Nitrogen (N2).

4 Water (H2O).

5 Carbon Dioxide (CO2).

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4. Compare the diagrams of the two substances shown below.
a. Use your understanding of structure to predict which substance is a gas at room temperature and which is a
at room temperature.
b. Explain your answer using your understanding of the relationship between structure and properties of
substances.
bond-
silicon atom
oxygen atom

Answers

Answer:

the anserw is 2

Explanation:

ОА
H+ HH
O H+ H → He
Oc He+
TH
Не
ODH +
Η
>

Answers

Ao H+HH OH

santa said he will eat shower curtian at 2 am

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