Animal cells extend lamellipodia to drive crawling motility when : a. GDP-rac is converted to GTP-rac, GTP-rac then activates WASP, activated WASP then binds and activates ARP2,3, which nucleates a network of straight actin filaaments which assemble with non-muscle myosin II to pull the plasma membrane forward
b. GDP-rac is converted to GTP-rac, GTP-rac then activates WASP, activated WASP then binds and activates ARP2,3, which nucleates a branch network of F-actin, which pushes the plasma membrane forward by a thermal ratchet mechanism
c. GDP-rac is converted to GTP-rac, GTP-rac then activates WASP, activated WASP then binds and activates ARP2,3, which nucleates a network of microtubules, which pushes the plasma membrane forward by a thermal ratchet mechanism
d. GDP-rac is converted to GTD-rac, GDP-rac then activates ADF/cofilin, activated ADF/cofilin then binds and activates ARP2,3, which nucleates a branch network of F-actin, which pushes the plasma membrane forward by a thermal ratchet mechanism

Answers

Answer 1

The correct answer is option B. GDP-Rac is converted to GTP-Rac which then activates WASP, which then binds and activates ARP2,3. This activates a branch network of F-actin, which pushes the plasma membrane forward by a thermal ratchet mechanism.

This process of extending lamellipodia to drive crawling motility requires that GTP-Rac be converted to GDP-Rac. This conversion is facilitated by WASP, and ARP2,3 is then activated which nucleates a branch network of F-actin. This branch network of F-actin then pushes the plasma membrane forward by a thermal ratchet mechanism.

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Related Questions

1. Make some conclusions about Eutrophication where excess nutrient runoff causes overgrowth of algae. Read the section on eutrophication in your lab book for more information.
a. What are some ways that humans add excess nitrogen and phosphorus to freshwater ecosystems? b. Explain why added phosphorus or nitrogen can lead to an overgrowth of algae and cyanobacteria. Use your data and observations from the lab to help support your answer. c. Explain how overgrowth of algae and cyanobacteria can the lead to the death of fish in these ecosystems. Again, use your data and observations from the lab to help with your explanation. 2. Toxins! a. Explain how biomagnification occurred in this exercise. Using your data compare how toxins accumulate at different trophic levels over the three-year time period. Explain why there are differences between the lower and higher trophic levels.
b. What other higher-level consumers feed on fish? What would you predict the toxin levels would be in their tissues? c. Describe the effect of mercury toxicity on humans. Do an internet search for information. Cite the resource you use.

Answers

Eutrophication is a process that occurs when excess nutrients, such as nitrogen and phosphorus, enter a freshwater ecosystem and cause an overgrowth of algae and cyanobacteria. This can have negative impacts on the health of the ecosystem, including the death of fish.

The Answer for Question 1a - 1c

a. Humans can add excess nitrogen and phosphorus to freshwater ecosystems through the use of fertilizers in agriculture, the discharge of untreated sewage, and the runoff of animal waste from livestock operations.

b. Added phosphorus and nitrogen can lead to an overgrowth of algae and cyanobacteria because these nutrients are essential for their growth. When there are excess nutrients available, the algae and cyanobacteria can grow rapidly and form dense blooms that can cover the surface of the water and block sunlight from reaching other aquatic plants.

c. Overgrowth of algae and cyanobacteria can lead to the death of fish in these ecosystems because the dense blooms can deplete the oxygen levels in the water, making it difficult for fish to breathe. Additionally, when the algae and cyanobacteria die, their decomposition can further deplete oxygen levels, leading to a condition called hypoxia that can cause fish to suffocate.

The Answer for Question 2a - 2c

a. Biomagnification is the process by which toxins accumulate at higher levels of the food chain. In this exercise, toxins were found to accumulate at higher levels in the tissues of organisms at higher trophic levels, such as fish, compared to those at lower trophic levels, such as zooplankton. This is because the toxins are not easily broken down or excreted, so they accumulate in the tissues of organisms and are passed on to their predators when they are eaten.

b. Other higher-level consumers that feed on fish include birds, mammals, and humans. It is likely that the toxin levels in their tissues would be even higher than those found in fish, due to the process of biomagnification.

c. Mercury toxicity can have a variety of negative effects on humans, including damage to the nervous system, immune system, and kidneys. It can also cause developmental problems in fetuses and young children. One resource for information on mercury toxicity is the World Health Organization's website (https://www.who.int/news-room/fact-sheets/detail/mercury-and-health).

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1. A cell contains 4 metacentric, 4 acrocentric, and 2 submetacentric chromosomes. Under normal conditions, what percentage of the daughter cells after meiosis will have ___
a. 4 metacentric chromosomes?
b. 2 pairs of acrocentric and submetacentric each?
c. A pair of submetacentric chromosomes
d. 2 acrocentric chromosomes?

Answers

A cell contains 4 metacentric, 4 acrocentric, and 2 submetacentric chromosomes. Under normal conditions, what percentage of the daughter cells after meiosis will have:

a. 4 metacentric chromosomes?

Answer: 100%. During meiosis, homologous chromosomes are separated into daughter cells, so each daughter cell will have 2 metacentric chromosomes from the parent cell. Therefore, all daughter cells will have 4 metacentric chromosomes (2 from each parent).

b. 2 pairs of acrocentric and submetacentric each?

Answer: 0%. Each daughter cell will only have 1 pair of acrocentric chromosomes and 1 pair of submetacentric chromosomes, as they are separated during meiosis. Therefore, none of the daughter cells will have 2 pairs of each.

c. A pair of submetacentric chromosomes

Answer: 100%. Each daughter cell will have 1 pair of submetacentric chromosomes, as they are separated during meiosis. Therefore, all daughter cells will have a pair of submetacentric chromosomes.

d. 2 acrocentric chromosomes?

Answer: 100%. Each daughter cell will have 2 acrocentric chromosomes (1 pair), as they are separated during meiosis. Therefore, all daughter cells will have 2 acrocentric chromosomes.

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What do proteins, polysaccharides and nucleic acids have incommon?Briefly describe endosymbiosis?

Answers

Proteins, polysaccharides, and nucleic acids are all types of biomolecules that are essential to living organisms. Endosymbiosis is the process by which one organism lives inside another organism and both benefit from the relationship.

One common feature they share is that they are all made up of smaller building blocks, or monomers, that are bonded together to form larger structures. Proteins are made up of amino acids, polysaccharides are made up of simple sugars, and nucleic acids are made up of nucleotides.

This is most commonly seen in the relationship between mitochondria and eukaryotic cells. Mitochondria are thought to have once been free-living bacteria that were engulfed by a larger cell. Over time, the mitochondria became an integral part of the larger cell, providing it with energy in the form of ATP. In return, the larger cell provided the mitochondria with a protected environment and the necessary nutrients. This mutually beneficial relationship is an example of endosymbiosis.

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T.F Tetanus is characterized by painful muscle spasms that can lead to respiratory failure and death is primarily resulting fromstimulating neurotransmitter releaseinhibiting neurotransmitter release.

Answers

True, tetanus is characterized by painful muscle spasms that can lead to respiratory failure and death. This is primarily due to the inhibition of neurotransmitter release.

Tetanus is caused by the bacteria Clostridium tetani, which produces a toxin called tetanospasmin. This toxin blocks the release of neurotransmitters that are responsible for inhibiting muscle contractions, leading to the characteristic spasms and stiffness associated with tetanus. Without proper treatment, these muscle spasms can interfere with breathing and lead to respiratory failure and death.

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Is it possible to synthesize more oxaloacetate than you started with if you feed the system acetyl-CoA? Why or why not?

Answers

Yes, it is possible to synthesize more oxaloacetate than you started with if you feed the system acetyl-CoA. This is because acetyl-CoA can be used to produce oxaloacetate through the citric acid cycle, also known as the Krebs cycle.

The citric acid cycle is a series of reactions that occur in the mitochondria of cells and produce energy in the form of ATP. Acetyl-CoA is an important molecule in this cycle, as it combines with oxaloacetate to form citrate, which then goes through a series of reactions to regenerate oxaloacetate.
Therefore, if you feed the system more acetyl-CoA, it will lead to the production of more oxaloacetate through the citric acid cycle. This is important for the cell, as oxaloacetate is a key molecule in many metabolic pathways, including the synthesis of amino acids and the production of glucose.
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Chinook Salmon tend to be very large or very small. Medium sized salmon are not strong enough to fight off large salmon, but also not small enough to sneak in and fertilize eggs without getting caught.






What type of Natural Selection has occurred?

Question 3 options:

disruptive selection


diagonal selection


stabilizing selection


directional selection

Answers

Disruptive selection is the kind of natural selection that has taken place in this situation.

Option A is correct

What does Natural Selection entail?

The process that drives species evolution over time is known as natural selection. It is based on the idea of "survival of the fittest," which states that people who have certain good qualities are more likely to live and reproduce, passing those qualities on to their children. When a population exhibits variation that is heritable, natural selection takes place.

People who have characteristics that are better suited to their environment, such as those that enable them to find food or avoid predators, have a greater chance of survival and reproduction in natural selection than those who have characteristics that are less favorable. The population's frequency of desirable traits rises over time, while its frequency of undesirable traits decreases.

Incomplete question :

Chinook Salmon tend to be very large or very small. Medium sized salmon are not strong enough to fight off large salmon, but also not small enough to sneak in and fertilize eggs without getting caught.

What type of Natural Selection has occurred?

Question 3 options:

A.disruptive selection

B.diagonal selection

C.stabilizing selection

D.directional selection

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Explain the steps by which a protein that is produced by a ribosome on the rough endoplasmic reticulum travels to exit the cell through exocytosis. Your answer should include the terms lumem, transport vesicle, Golgi complex, and secretory vesicle.

Answers

The process by which a protein produced by a ribosome on the rough endoplasmic reticulum travels to exit the cell through exocytosis is a complex one.

It begins with the protein entering the lumen of the rough endoplasmic reticulum. From there, the protein is packaged in a transport vesicle and then sent to the Golgi complex.

At the Golgi complex, the protein is processed further, modified, and packaged in a secretory vesicle.

The secretory vesicle then moves to the cell membrane, where it fuses with it and releases the protein from the cell in a process called exocytosis.

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The density (rho) of blood is about 1060 kg/m3. The viscosity (μ) of blood normally averages 3 x 10-3 Pa sec. There are blood vessels in the body in varying size. Typically, the velocity of blood decreases with inner diameter of the vessel, as implied in the table below:
Vessel type
Inner diameter (D, cm)
Blood flow velocity (v, cm/sec)
Elastic arteries
2.5
34
Muscular arteries
1.2
17
Arterioles
0.25
3
Venules
0.2
2
Veins
1.5
7
Calculate the Reynolds number for blood flow in all these different types of blood vessels. In the different vessels, is there laminar or turbulent flow present?

Answers

In the different vessels, the elastic arteries and muscular arteries, there is turbulent flow present, while in the arterioles, venules, and veins, there is laminar flow present.

The Reynolds number is a dimensionless number that is used to determine the type of flow in a fluid. It is given by Re = (ρvD)/μ, where ρ is the density of the fluid, v is the velocity of the fluid, D is the diameter of the vessel, and μ is the viscosity of the fluid.

For the elastic arteries:

Re = (1060 kg/m³)(34 cm/sec)(2.5 cm)/(3 x [tex]10^{-3}[/tex] Pa sec)

= 1.86 x 104

For the muscular arteries:

Re = (1060 kg/m³)(17 cm/sec)(1.2 cm)/(3 x [tex]10^{-3}[/tex] Pa sec)

= 1.01 x 104

For the arterioles:

Re = (1060 kg/m³)(3 cm/sec)(0.25 cm)/(3 x [tex]10^{-3}[/tex] Pa sec)

= 2.5 x 102

For the venules:

Re = (1060 kg/m³)(2 cm/sec)(0.2 cm)/(3 x [tex]10^{-3}[/tex] Pa sec)

= 1.7 x 102

For the veins:

Re = (1060 kg/m³)(7 cm/sec)(1.5 cm)/(3 x [tex]10^{-3}[/tex] Pa sec)

= 6.1 x 103

In general, laminar flow occurs for Re < 2000, and turbulent flow occurs for Re > 4000. Therefore, in the elastic arteries and muscular arteries, there is turbulent flow present, while in the arterioles, venules, and veins, there is laminar flow present.

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1. What is a mutation?
2. Are most mutations repaired? Briefly explain.
3. Briefly explain the disorder called cystic fibrosis and
determine if it is a dominant or recessive trait.
4. Describe the dif

Answers

A mutation is a change in the DNA sequence of a gene or chromosome. Most mutations are repaired by the cell's DNA repair mechanisms. Cystic fibrosis is a genetic disorder that affects the respiratory and digestive systems.  The difference between a dominant and recessive trait is that a dominant trait only requires one copy gene to be expressed, while a recessive trait requires two copies of the gene.

Mutation can occur spontaneously or be caused by external factors such as exposure to radiation or chemicals. Most mutations are repaired by the cell's DNA repair mechanisms. However, some mutations may not be repaired and can be passed on to future generations, potentially causing genetic disorders or diseases.

Cystic fibrosis caused by a mutation in the CFTR gene, which affects the production of a protein that regulates the movement of salt and water in and out of cells. As a result, thick mucus can build up in the lungs and pancreas, leading to infections and digestive problems. Cystic fibrosis is a recessive trait, meaning that an individual must inherit two copies of the mutated gene in order to develop the disorder. The difference between a dominant and recessive trait can show by this example, if a person inherits one copy of a dominant gene for a certain trait, they will express that trait. However, if a person inherits one copy of a recessive gene, they will not express the trait unless they also inherit a second copy of the gene.

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Question 9 2 pts What kind of test is routinely used to detect HIV? GWAS/SNP array Sandwich antibody test Competitive antigen/antibody test Hybridization probe Question 10 2 pts Which of these is NOT a way that SNP microarrays are used? To detect differences in DNA fragment lengths To detect SNPs associated with cancers To detect loss of heterozygosity in tumors To determine whether a person is missing an allele

Answers

The Hybridization probe test is routinely used to detect HIV. The option that is not a way that SNP microarrays are used is "To detect differences in DNA fragment lengths".

What is the sandwich antibody test?

The sandwich antibody test is an immunoassay used to detect antibodies or antigens in a sample. Sandwich ELISA is a kind of immunoassay that uses two monoclonal antibodies instead of one to identify and quantify specific proteins or other molecules. In sandwich ELISA, one antibody is immobilized on a solid surface, while the other is labeled and used to detect the target protein or antigen.

A competitive antigen/antibody test is a kind of assay that detects the presence of an antibody in a serum sample. SNP microarrays SNP microarrays are microarrays that are used to detect the presence of single-nucleotide polymorphisms (SNPs) in DNA sequences. SNP microarrays can be used to analyze genomic DNA for variations in allele frequencies, which can be used to study human populations and evolution, as well as to identify disease-causing mutations. The option that is not a way that SNP microarrays are used is "To detect differences in DNA fragment lengths." In general, SNP microarrays are used to detect the presence or absence of particular alleles rather than differences in DNA fragment lengths.

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why
fossils were deposited at the same time and why might might this
create problems for geogolist

Answers

Fossils were deposited at the same time because of a geological event such as a flood, volcanic eruption, or landslide that rapidly buried the organisms.

This can create problems for geologists because it can make it difficult to accurately determine the age of the fossils and the geological strata they are found in. If multiple organisms from different time periods are buried together, it can create a confusing and inaccurate geological record.

This is why geologists use a variety of methods, including relative dating and radiometric dating, to accurately determine the age of fossils and the geological strata they are found in.

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Can you please help me answer the following questions please.
4. A _______________ B cell is a type of B cell that reacts to the presence of an antigen by becoming a plasma B cell.
5. An _______________ vaccine is a vaccine made from viruses and bacteria that have been killed through physical or chemical processes. These killed organisms cannot cause disease.
6. _______________ refers to the development of antibodies in the blood of an individual who previously did not have detectable antibodies.
7. A _______________ killer T cell is a type of T cell that reacts to the presence of an antigen by quickly recognizing and destroying already infected cells, preventing the further spread of an infection.
8. A _______________ vaccine contains antigens that are chemically inactivated toxins.

Answers

4. A naive B cell is a type of B cell that reacts to the presence of an antigen by becoming a plasma B cell.
5. An inactivated vaccine is a vaccine made from viruses and bacteria that have been killed through physical or chemical processes. These killed organisms cannot cause disease.
6. Seroconversion refers to the development of antibodies in the blood of an individual who previously did not have detectable antibodies.
7. A cytotoxic killer T cell is a type of T cell that reacts to the presence of an antigen by quickly recognizing and destroying already infected cells, preventing the further spread of an infection.
8. A toxoid vaccine contains antigens that are chemically inactivated toxins.

Naive B cells respond to antigens by becoming plasma B cells, which produce antibodies. This is an important aspect of the adaptive immune system that helps the body fight off infections.

Inactivated vaccines are a safe and effective way to protect against infectious diseases. Because the organisms used to make the vaccine are killed, there is no risk of getting sick from the vaccine itself.

Seroconversion is a key indicator of an effective immune response. It shows that the body has successfully recognized and responded to an antigen, which is important for developing immunity against future infections.

Cytotoxic killer T cells play a critical role in the immune response by identifying and destroying infected cells. This is important for preventing the spread of infectious agents throughout the body.

Toxoid vaccines are a type of vaccine that use inactivated toxins to stimulate an immune response. This is an effective way to prevent diseases caused by bacterial toxins, such as tetanus and diphtheria.

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discuss the bioethical implications of germline genetic
enhancement.
pros and cons

Answers

The bioethical implications of germline genetic enhancement are a topic of much debate in the scientific community. Germline genetic enhancement refers to the process of manipulating genes in the germline cells (i.e. the cells that will pass on genetic information to future generations) in order to create offspring with specific desired traits.


Pros:
1. Germline genetic enhancement could potentially lead to the elimination of certain genetic diseases or disorders, leading to a healthier population.
2. It could also lead to the enhancement of certain beneficial traits, such as intelligence, physical strength, or disease resistance, potentially improving quality of life for individuals and society as a whole.
3. It could also allow parents to give their children the best possible start in life, potentially leading to a more successful and fulfilling life for the individual.
Cons:
1. One of the biggest concerns is the potential for creating a new form of social inequality, where those who can afford to undergo germline genetic enhancement have an unfair advantage over those who cannot.
2. There is also a fear that germline genetic enhancement could lead to a "slippery slope" where individuals begin to make increasingly extreme and potentially harmful modifications to their genes.
3. There are also concerns about the potential for unforeseen consequences of germline genetic enhancement, such as unintended health problems or unexpected effects on future generations.
Overall, the bioethical implications of germline genetic enhancement are complex and multifaceted, and there is much debate about the potential pros and cons of this technology.

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What is a saliva collecting in corners of the mouth causing buildup microorganisms that look like painful sores on the corner of the mouth

Answers

Saliva collecting in the corners of the mouth and causing a buildup of microorganisms that look like painful sores is called angular cheilitis. This condition is also known as perleche or angular stomatitis.

Angular cheilitis is caused by a fungal or bacterial infection, and is more common in people with weakened immune systems, such as those with diabetes or HIV. It can also be caused by a vitamin deficiency, such as a lack of vitamin B2 or iron.
To treat angular cheilitis, a healthcare professional may recommend antifungal or antibacterial creams, as well as supplements to address any vitamin deficiencies. It is also important to keep the affected area clean and dry to prevent further infection.
In summary, angular cheilitis is a condition in which saliva collects in the corners of the mouth, causing a buildup of microorganisms that can lead to painful sores. It is caused by a fungal or bacterial infection, and can be treated with antifungal or antibacterial creams, as well as supplements to address any vitamin deficiencies.

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how can you change the viscosity of alginate gel? provide
advantages and disadvantages of using very viscous vs using not
viscous gel

Answers

The viscosity of alginate gel can be changed by adjusting the ratio of sodium alginate to water. The advantages of using a very viscous alginate gel are that it is more resilient and less likely to be disturbed. On the other hand, the disadvantage is that it can be difficult to work with and may require more time and energy to manipulate.

The advantages of using a less viscous alginate gel are that it is easier to work with and requires less time and energy to manipulate. However, the disadvantage is that it is less resilient and more likely to be disturbed and has less ability to form detailed molds and a potentially runny consistency if not mixed properly.

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How would an inducible operon, such as the lac operon, function if the repressor protein and inducer molecule had a very strong or secure bond? How might this strong bond affect the production rate of the products of the operon? Would those products be at a high or low concentration within the cell? Finally, under what circumstances would this system be beneficial for the cell?

Answers

An inducible operon, such as the lac operon, functions by producing proteins only when they are needed.

The repressor protein binds to the operator site of the operon, preventing the production of the proteins. However, when an inducer molecule is present, it binds to the repressor protein, causing it to release from the operator site and allowing the production of the proteins.

If the repressor protein and inducer molecule had a very strong or secure bond, it would be more difficult for the inducer molecule to release the repressor protein from the operator site.

This would result in a lower production rate of the products of the operon, leading to a low concentration of those products within the cell.

This system would be beneficial for the cell under circumstances where it is necessary to tightly regulate the production of the proteins.

For example, if the products of the operon are toxic to the cell in high concentrations, a strong bond between the repressor protein and inducer molecule would help to prevent the overproduction of those products.

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Fats and steroids are examples of which macromolecule?

Carbohydrates
Lipids
Proteins
Nucleic acids

Answers

Answer:

Lipids

Explanation:

Lipids include fats, waxes, oils, steroids, and more.

Lipids

Lipids included fats, oils, steroids etc..

What two alleles of gene C control hair color in horses C1 and C2?

Answers

The two alleles of gene C that control hair color in horses are C^CR and C^C.

The C^CR allele is dominant and produces a chestnut or red coat color, while the C^C allele is recessive and produces a black coat color. When a horse has two copies of the C^CR allele, it will have a chestnut or red coat. When a horse has one copy of the C^CR allele and one copy of the C^C allele, it will also have a chestnut or red coat. However, when a horse has two copies of the C^C allele, it will have a black coat.

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PLEASE HELP!!!!!!! WILL MARK BRAINLIST IF ANSWER IS CORRECT!!!

Answers

The mutation shown is a substitution of nucleotides in the codon ATC which codes for the amino acid isoleucine to the codons ACT and ACC which codes for the amino acid threonine.

What is a mutation?

A mutation is a change that takes place in the sequence of our DNA as a consequence of errors made during DNA replication or environmental variables like UV light and cigarette smoke.

The nucleotide bases A, C, G, and T in our DNA can alter or "mutate" over the course of a lifetime.

The proteins produced change as a consequence of this. This may be advantageous or detrimental.

If mistakes are made during DNA replication and they are not immediately fixed, mutations may result.

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What is NOT a critical ingredient in the estimation of the time of origin of HIV? Sampling strains from different patients at different times since the early stage of the pandemic. Isolating the viral

Answers

In fact, later research found that SIVmac wasn't a typical pathogen of... Calculating the timescale for the AIDS virus's origins and evolution.

What number of AIDS viruses exist?

Some monkeys or big apes can contract HIV-1 and HIV-2 as well as a number of other similar viruses. Whereas HIV-1 is widespread, HIV-2 is nearly entirely restricted to West Africa. HIV-1 is more easily transferred than HIV-2, so HIV-1 infection leads to AIDS more quickly.

What's the origin of the AIDS virus?

Early in the 20th century, the HIV virus, which causes AIDS, had spread from chimpanzees to humans in Africa. The first known instance of HIV-1 infection is human blood was discovered in 1959 and came from a sample collected from a man who had passed away in Kinshasa, 

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The basic units of information that encode the proteins needed
to grow and function as a living organism are called___.

Answers

A gene is a specific place on a chromosome that contains an organised sequence of nucleotides that codes for a particular functional protein.

What are the fundamental units of information that code the proteins required for an organism to develop and function?

The instructions required for a creature to grow, endure, and reproduce are encoded in its DNA. DNA sequences must be transformed into messages that can be utilised to create proteins, which are the complex molecules that carry out the majority of the work in our bodies, in order to perform these activities.

What is the name of the region of the genome that codes for proteins?

Exons are the regions of DNA (or RNA) that code for proteins. Following transcription, fresh, immature messenger RNA strands known as pre-mRNA may have both.

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1. Outline and describe the two (2) checkpoints that determine
the fate of B cells during development in
the bone marrow.
2. Draw and describe the process by which self-reactive immature
B cells are p

Answers

1. The two checkpoints that determine the fate of B cells during development in the bone marrow are the pre-B cell receptor checkpoint and the B cell receptor checkpoint.


2. The process by which self-reactive immature B cells are prevented from maturing and potentially causing autoimmune disease is called negative selection.

1. The pre-B cell receptor checkpoint ensures that the B cell has successfully rearranged its heavy chain gene segments to produce a functional pre-B cell receptor. If this checkpoint is passed, the B cell can proceed to the next stage of development.

The B cell receptor checkpoint ensures that the B cell has successfully rearranged its light chain gene segments to produce a functional B cell receptor. If this checkpoint is passed, the B cell can proceed to the next stage of development and eventually leave the bone marrow to mature in the spleen.

2. This process involves the testing of the B cell receptor for self-reactivity.

If the B cell receptor binds to self-antigens with high affinity, the B cell undergoes one of three fates: receptor editing, anergy, or apoptosis. Receptor editing involves the rearrangement of the light chain gene segments to produce a new B cell receptor that is not self-reactive.

Anergy involves the inactivation of the B cell so that it cannot respond to antigen stimulation. Apoptosis involves the programmed cell death of the B cell. Through these mechanisms, negative selection ensures that self-reactive B cells do not mature and cause autoimmune disease.

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Which biotherapeutic category could be used to treat type I Diabetes?
Group of answer choices
A. Vaccine
B. Recombinant Protein
C. Cell Therapy
D. Monoclonal antibodies
E. A and C
F. B and C

Answers

Type I diabetes is a disease that affects a person's pancreas. The question at hand is which biotherapeutic category could be used to treat type I diabetes? B. Recombinant protein is the biotherapeutic category that could be used to treat type I Diabetes.

A type of biotherapy that could be used to treat type I diabetes is recombinant protein. A protein made through genetic engineering is called a "recombinant protein."

It can be the product of a cloned gene that is being expressed in a foreign host cell, or it can be a protein that has been changed by adding a specific DNA sequence from the genome of another organism.

Diabetes type 1 is also called diabetes that needs insulin. This kind of diabetes happens when your immune system attacks and kills the cells in your pancreas that make insulin.

Insulin is a hormone that controls how much sugar is in your blood. Type 1 diabetes is treated with insulin therapy. It helps you keep your blood sugar under control.

Therefore, The question at hand is which biotherapeutic category could be used to treat type I diabetes? B. Recombinant protein

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3) A new mutation is at a frequency of 0.02 and it is slightly favored by selection (s = 0.001). Would you expect it to have a higher probability of reaching fixation in population with large Ne, small Ne, or equal probability in both? Why?

Answers

Numerous variables, such as the mutation rate, the strength of selection, and the effective population size, affect the likelihood that a new mutation will become fixed in a population (Ne).

Would you expect it to have a higher probability of reaching fixation in population with large Ne, small Ne, or equal probability in both? Why?

In this case, the new mutation has a frequency of 0.02, and selection is slightly favouring it with s = 0.001. With a frequency of 0.02, a mutation still has a low frequency in the population and is highly likely to be lost due to genetic drift. However, the fact that selection favours it only marginally suggests that it has a selective advantage and will become more prevalent over time. The likelihood that the new mutation will fixation is significantly influenced by the effective population size (Ne). Because genetic drift, which can cause random fluctuations in allele frequencies, is diminished by a larger Ne, fixation is generally more likely. As a result, we can anticipate that the new mutation will be more likely to fixate in a population with a large Ne than in a population with a small Ne. In conclusion, a population with a large Ne is more likely to reach fixation than a population with a small Ne for a new mutation with a frequency of 0.02 and a slight selective advantage (s = 0.001).

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Discuss three new legal responsibilities that Grade 12 learners could have to honour in order to effectively navigate through life after they have turned eighteen for meaningful contribution to society

Answers

When Grade 12 learners turn eighteen, they become legal adults and assume new legal responsibilities that come with adulthood.

Voting: The ability to vote is one of the most significant legal obligations of adulthood. Students in Grade 12 have a responsibility to exercise their right to vote in municipal, provincial, and federal elections in order to participate in the democratic process.

Taxes must be paid, which is a crucial legal obligation for adults. Students in grade 12 are expected to begin making money from their occupations, which means they will need to file tax returns and pay income tax. Public services including healthcare, education, and social welfare programs are paid for through taxes.

Jury duty: As a legal obligation that comes with age, students in grade 12 may be asked to serve on a jury.

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Changes in the skin often serve as the most immediately noticeable signs of aging for humans.
Explain how each of the following cells or molecules relate to a symtom of aging in the skin:
- keratinocytes
- fibroblasts
- collagen/ elastin
-lipids

Answers

Changes in the skin often serve as the most immediately noticeable signs of aging for humans. The following cells or molecules keratinocytes, fibroblast, collagen/ elastin, and lipids relate to a symtom of aging in the skin when the ability of cells decreases it will cause reduced elasticity so that wrinkles or wrinkles appear on the skin

The skin is made up of several different cells and molecules, each cells or molecules plays a role in the aging process. Keratinocytes are the primary cells of the epidermis, the outermost layer of the skin. As we age, the production of keratinocytes slows down, leading to thinner and more fragile skin. This can result in wrinkles and an increased risk of injury. Fibroblasts are responsible for the production of collagen and elastin, two proteins that give the skin its strength and elasticity. As we age, the production of these proteins decreases, leading to a loss of elasticity and the development of wrinkles.

Collagen and elastin are the primary structural proteins in the skin. As we age, the production of these proteins decreases, leading to a loss of elasticity and the development of wrinkles. This can also result in sagging skin and a loss of firmness. Lipids are important for the health of the skin, as they help to keep it hydrated and protect it from damage. As we age, the production of lipids decreases, leading to dry and fragile skin. This can also result in an increased risk of injury and a loss of elasticity.

Overall, changes in the skin are a natural part of the aging process. However, by understanding the role of different cells and molecules in the skin, we can better understand the symptoms of aging and take steps to protect and maintain healthy skin.

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Lipids and Lipid Metabolism Case Study
An 86-year old man with moderate cognitive impairment, double knee and hip replacements, and history of type-2 diabetes, hypercholesterolemia, and mild hypertension (all under control with medications) complains of upset abdomen and is refusing to eat or drink. He is unable to accurately describe the location of the pain or food that trigger the pain. He subsequently begins having bouts of vomiting. He is transferred from his long-term care home to the hospital emergency room. The ER physician orders standard blood work that include a blood cell analysis, liver function and inflammation parameters.
Blood Tests
Parameter
Patient Values
Normal Range
ALT
72 IU/L
17–63 IU/L
AST
45 IU/L
15–37 IU/L
ALP
140 IU/L
50–136 IU/L
Albumin
33 g/L
34–50 g/L
Total Protein
65 g/L
65–78 g/L
Bilirubin
14 μmol/L
2–9 μmol/L
GGT
89 IU/L
15.0–85.0 IU/L
C-reactive protein
36 mg/L
≤ 10 mg/L
Question 1. What general problem do these blood values indicate?
The ER physician orders an abdominal ultrasound which indicates that the gentleman has numerous gall stones in his gallbladder.
Question 2. What is the composition of gall stones?
Question 3. How do gall stones form?
Question 4. What impact (on overall health and specifically the digestion of food) would a gall bladder full of gall stones have for an individual?
The gentleman is admitted to the surgery unit of the hospital and is presented with the following options: 1) a nasogastric scope procedure (non-surgical) to clean out the bile duct of any stones and sphincterectomy of the sphincter of Oddi or 2) surgical removal of the gall bladder.
Question 5. Knowing what you do about GI tract physiology and function as well as lipid digestion and absorption, what would the impact of each of these procedures on the individuals future food digestion and absorption?
Question 6. What procedural/surgical option would you recommend to this individual and why?

Answers

1. The blood values indicate that there is a problem with the liver and gallbladder. The elevated levels of ALT, AST, ALP, Bilirubin, and GGT suggest liver damage or inflammation. The low levels of albumin and total protein also indicate liver dysfunction.

2. Gallstones are composed of cholesterol, bilirubin, and calcium salts.

3. Gallstones form when there is an imbalance in the substances that make up bile, leading to the formation of crystals that can grow into stones.

4. A gallbladder full of gallstones can cause blockages in the bile ducts, leading to pain, inflammation, and infection. It can also impact the digestion of fats, as bile is necessary for the emulsification and absorption of lipids.

5. The nasogastric scope procedure would remove any stones blocking the bile ducts and allow for the normal flow of bile, improving digestion and absorption of fats. The surgical removal of the gallbladder would also remove the source of the stones, but may lead to changes in the way fats are digested and absorbed, as there would no longer be a storage organ for bile.

6. It is ultimately up to the individual and their healthcare team to decide on the best option. However, the nasogastric scope procedure may be a less invasive option that could provide immediate relief without the need for surgery. The surgical removal of the gallbladder may be a more permanent solution, but could also lead to changes in digestion and absorption of fats.

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Linnaeus and other early scientists classified organisms based on visible traits. Today, scientists generally use cladograms based on DNA and other evolutionary evidence to classify organisms. Why have most scientists changed their method of classification?

Answers

Answer:

DNA is a

Explanation:

1. Answer the following characteristics for Chytridiomycota
Fungi.
A. Color
B. Texture
C. Form
D. Size
E. Starch storage (where)

Answers

Chytridiomycota Fungi:
A. Color: range in color from white to gray to black.
B. Texture: slimy or a leathery texture.
C. Form: typically single-celled organisms.
D. Size: microscopic.
E. Starch storage (where): in their cell walls.

A. Color: It is not possible to give a specific color description to these fungi. Their color varies from greenish, yellow, brown to black.

B. Texture: They have a soft and pliable texture.

C. Form: These fungi have various forms ranging from single celled to simple multicellular structures.

D. Size: The size of chytridiomycota varies from 2-7mm in diameter

E. Starch storage (where): Their energy reserves are stored in the form of starch in the cytoplasm of the cell.

Chytridiomycota are one of the phyla under kingdom Fungi. They are the most primitive fungi and have different characteristics than the other fungi. They are saprophytic and parasitic in nature. They can be found in various aquatic and terrestrial habitats.

Chytridiomycota are characterized by their unique flagellated zoospores. They are the only fungi that produce motile spores. These fungi are responsible for causing diseases in aquatic animals and amphibians.

Their life cycle is characterized by the alternation of haploid and diploid phases. They reproduce sexually and asexually. They have different forms and are found in different sizes ranging from 2-7mm in diameter. They do not have any fruiting body structures like other fungi. They store their energy in the form of starch in the cytoplasm of the cell.

They are mostly found in decomposing organic matter and water. They are the primary decomposers of organic matter in aquatic ecosystems. They are also responsible for the decomposition of cellulose in the stomach of ruminants.

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According to your textbook, concern about women's health and interaction with health professionals contributed to the birth of modern bioethics. True False
According to your textbook, the development

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The statement "According to the textbook, concern about women's health and their interaction with health professionals was one of the factors that contributed to the birth of modern bioethics" is True.

This is because women's health issues, such as reproductive rights and access to healthcare, have been at the forefront of ethical debates in the medical field. As a result, modern bioethics has emerged as a field that focuses on the ethical implications of medical practices and healthcare policies, with a particular emphasis on the rights and well-being of women.

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