A mutation in the gene coding for a single-polypeptide enzyme results in the substitution of the amino acid serine, which has a polar R group, by the amino acid phenylalanine, which has a nonpolar R group. When researchers test the catalysis of the normal enzyme and the mutated enzyme, they find that the mutated enzyme has much lower activity than the normal enzyme does. Which of the following most likely explains how the amino acid substitution has resulted in decreased catalytic activity by the mutated enzyme?
A The substitution decreased the mass of the enzyme so that the mutated enzyme binds more weakly to the substrate than the normal enzyme does.
B The substitution altered the secondary and tertiary structure of the enzyme so that the mutated enzyme folds into a different shape than the normal enzyme does.
C The substitution caused many copies of the mutated enzyme to cluster together and compete for substrate to bind.
D The substitution caused the directionality of the enzyme to change such that the amino terminus of the normal enzyme has become the carboxy terminus of the mutated enzyme.

Dysregulated translational factors and epigenetic regulation interact in B cells and contribute to autoimmune disease.

B cells play an important role in antigen presentation, antibody production, and secretion of pro-/anti-inflammatory cytokines in adaptive immunity. Several translation factors, including transcription factors and cytokines, are involved in regulating B cell development in concert with epigenetic regulation. Autoimmune diseases are generally characterized by autoreactive B cells and highly pathogenic autoantibodies. Successful B-cell depleting therapies in mouse models and clinical studies demonstrate the role of B cells in the pathogenesis of autoimmune diseases. Failure of B-cell tolerance at immune checkpoints results in the accumulation of autoreactive naive B (BN) cells with aberrant B-cell receptor signaling and dysregulated B-cell responses, leading to autoantibody-mediated autoimmune responses.

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Answer:

the central nervous system uses these synapses to transfers electrical impulses to the brain through the spinal cord.

Explanation:

For example a stimulus such as bright light is detected by receptor cells, this sends electrical impulses through the sensory neurons and passes them through synapses to relay neurons. The gap between these neurons are called synapses which use neurotransmitters (chemicals) to send the impulse over the gap. Lots of these synapses are in the spinal cord and brain so that more of these impulses can be received and therefore a motor neuron can send an impulse to an effector so a response can be issued, for this example the response would be closing the eyes so that the bright light doesn't damage the eyes- this is an example of a reflex action.

Sorry if this doesn't make sense or I've explained it wrong! I hope I've helped in the slightest!

There are huge number of synapses in the spinal cord and the brain as these synapses are used by the central nervous system to send electrical impulses to the brain via the spinal cord.

To illustrate, when a stimulus like as strong light is received by receptor cells, electrical impulses are sent by sensory neurons and sent across synapses to relay neurons. Synapses are the gaps between these neurons that employ neurotransmitters (chemicals) to transfer the impulse across the gap. A lot of these synapses are in the spinal cord and brain so that more of these impulses can be received and thus a motor neuron can send an impulse to an effector so that a response can be issued, for example, closing the eyes so that the bright light does not damage the eyes- this is an example of a reflex action.

As a conclusion, as synapses are employed by the central nervous system to transfer electrical impulses to the brain via the spinal cord, we may assume that there are a large number of synapses in the spinal cord and brain.

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Answer:

D

Explanation:

Transcription = DNA to RNA

Translation = RNA to codons to create amino acids or proteins.

BELIEFS: In Japan, it is believed that folding 1000 paper cranes can grant a person a wish.

• AESTHETIC: In the Himba tribe of Namibia, women cover their skin with a mixture of butterfat and ochre to enhance their beauty and protect their skin from the sun.

• EDUCATION: In some parts of India, the Guru-shishya tradition is still practiced, where a student lives with and learns from a Guru (teacher) in a specific field, such as music or martial arts.

• RELIGION: In Bali, Indonesia, daily offerings and prayers are made to the gods and ancestors, often including small intricate woven baskets filled with rice, flowers, and other items.

• MATERIAL CULTURE: In the Inuit community of the Arctic, igloos were traditionally made as temporary shelters out of snow and ice blocks.

Culture in the above sense refers to the shared beliefs, values, customs, behaviors, and artifacts that characterize a group or society. It encompasses various aspects of human society, including beliefs and traditions, language, religion, art and aesthetics, education, and material culture.

Culture can be defined as a way of life of a particular group of people and is passed down from generation to generation through socialization.

In the examples provided above, different cultural practices are discussed in relation to the given elements such as beliefs, aesthetic, education, religion and material culture. For example, the practice of folding 1000 paper cranes in Japan is a cultural belief that is passed down through generations.

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Explanation:

The formula for the volume of a cylinder is V=Bh or V=πr2h . The radius of the cylinder is 8 cm and the height is 15 cm. Substitute 8 for r and 15 for h in the formula V=πr2h .

Answer:

if mushrooms were producers the bear and tree population would also increase

Answer:

4/D

Explanation:

It would be Pp, genotypes like that are closed heterozygous because 1 allele (P) is dominate, while the other is recessive (p). It could also be called a hybrid.

Answer:

b. 50% chance of yellow skin

Explanation:

The likelihood that their kid will have yellow skin depends on the genetic makeup of both Patterson and Petunia. Patterson has the genotype Pp, which means he has one dominant allele for pink body color and one recessive allele for yellow body color. Petunia, on the other hand, has the genotype pp, which means she is homozygous recessive for yellow body color.

When they have children, each parent will contribute one of their alleles to their offspring. The offspring will have a 50% chance of inheriting the recessive allele for yellow body color from Patterson and a 50% chance of inheriting the recessive allele for yellow body color from Petunia. Therefore, the likelihood that their kid will have yellow skin is 50%.

Answer: Carbohydrates on the cell membrane help cells function properly. Carbohydrates do this in two ways: helping cells recognize each other and providing protection for cells.

Reactions of photosynthesis:

Energy from Sunlight is used to breakdown Water in order to release electrons in order to synthesize ATP and NADPH from ADP and NADP+ in the light-dependent reaction that occurs in the chloroplast. Electron transport chain, photosystem I, photosystem II, and ATP synthase are the processes involved in this stage.

The light-independent stage, also known as the Calvin cycle, uses ATP, NADPH, and CO2 as reactants to produce SUGAR (glucose), NADP+, and ADP as products.

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Answer:

The reproductive system??

According to the rule of conservation of energy, energy can only be transformed from one form of energy to another and cannot be created or destroyed.

This indicates that unless energy is added from the outside, a system always has the same quantity of energy.

Energy conservation was different from mass conservation. However, special relativity demonstrates that mass and energy are connected by the formula E = mc², and science currently holds the belief that mass-energy is conserved as a whole. Theoretically, this means that every mass-containing object can transform into pure energy and vice versa. However, it is thought that this is only feasible under the most severe physical circumstances, such as those that probably occurred in the cosmos just after the Big Bang.

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Answer:

O happiness

Explanation:

According to this question, Dopamine is a neurotransmitter that makes a person feel happy when released in the brain. However, it is stated that certain drugs stop the synapses from removing neurotransmitters, like Dopamine.

Hence, when these drugs cause the amount of neurotransmitters in the synapses to be increased, this means that the response caused by those neurotransmitters will also be increased. For example, an increase in Dopamine will cause an increase in HAPPINESS.

Answer:

B. Happiness.

Explanation:

Each of the following would cause an increase in blood pressure except inhibitor of angiotensin II. So option c is correct.

Angiotensin II is a potent vasoconstrictor, which means it causes the walls of the arteries to narrow, leading to an increase in blood pressure. Inhibitors of this hormone, such as ACE inhibitors and ARBs, work by blocking its action and preventing it from constricting the arteries, leading to a decrease in blood pressure.

Blood pressure is a measure of the amount of force exerted against the walls of the arteries as blood flows through them. It is an important indicator of cardiovascular health as it can affect the function of various organs in the body. The most common causes of an increase in blood pressure include an increase in aldosterone, increase in peripheral resistance, inhibition of angiotensin II, and increase in blood volume.

One of the factors that would cause an increase in blood pressure is an increase in aldosterone. Aldosterone is a hormone produced by the adrenal glands that helps regulate the balance of fluids in the body. It acts on the kidneys to increase the reabsorption of sodium and the excretion of potassium. This causes an increase in blood volume, which in turn leads to an increase in blood pressure, specifically in the systolic pressure.

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Answer:

The water cycle is driven primarily by the energy from the sun. This solar energy drives the cycle by evaporating water from the oceans, lakes, rivers, and even the soil. Other water moves from plants to the atmosphere through the process of transpiration.

Explanation:

A possible claim based on the information provided could be:

The statement describes an experiment or observation that compared the count of normal liver cells to that of cancerous cells at different cell densities. The results showed that the count of normal liver cells remained relatively stable as the cell density increased, while the count of cancer cells increased at higher cell densities.

From this observation, the conclusion was drawn that cancer cells in the liver have lost the harmony and coherence that is typical of healthy tissue.

Therefore, this claim is based on the experiment/observation conducted and the comparison of the count of normal liver cells and cancer cells. It implies that cancer cells are behaving differently from normal cells in a way that makes them less orderly and more chaotic and thus different from healthy tissue.

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See full question below

Count of normal liver cells vs. cancerous cells.

Normal liver cells (lower curve) have a relatively stable count

at increasing cell density, while cancer cells of the same cell

type show an increased count at higher cell densities. From

this, it was concluded that populations of cancer cells have

lost the harmony and coherence that is typical for healthy

tissue. What claim can be obtained from the above statement.

Answer:

Hey mate.....

Explanation:

This is ur answer.....

Hope it helps!

Brainliest pls....

Follow me! ;)

Explanation:

Behavioral adaptation is something an animal does usually in response to some sort of external stimulus in order to survive. Hibernating during winter is an example of a behavioral adaptation,this is common among bears.Another behavioral adaptation is migration by birds .

The difference in diversity of species which are present in two different sites cannot be determined just be looking at the number of species.

The diversity of species or species diversity can be defined as the number of different species which are present in an ecosystem and also the abundance of those species. Species diversity changes with change in location.

There are several factors which determine the species diversity. These factors include competition amongst the species, genetic diversity, diversity in habitat etc. These factors can help us determine the difference in species diversity of different locations. We cannot conclude regarding diversity just by looking at the number of species.

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The parts of atoms include:

An atom is made up of a central nucleus and one or more negatively charged electrons. The nucleus is positively charged and contains one or more protons and neutrons, which are relatively heavy particles. Atoms are the fundamental constituents of matter.

Protons are made up of two up quarks and one down quark. Neutrons are made up of one up quark and two down quarks. The "strong nuclear force," one of the four fundamental forces, holds the nucleus together.

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Answer:

MRNA ou RNA?

Explanation:

Artificial selection is the identification by humans of desirable traits in plants and animals, and the steps taken to enhance and perpetuate those traits in future generations.

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Joe's reading on the orange scale shows an example of the scientific law of mass conversion.

The law of mass conservation is a law that states that mass is eternal. the law of conservation of mass states that matter or mass cannot be created or destroyed but can be changed into other forms such as liquids, gases, as well as solids.

For example, when someone burns wood. The mass of burning wood is not destroyed. However, it changes form to charcoal, ash, and smoke with the same total mass.

Likewise, what Joe did when he read the mass scale of the orange before and after it was cut, the mass did not change.

This question is optional:

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Few trees should be left standing, and the landowner should let nature take its course.

A forest can quickly undergo organic regeneration through the growth of grass and herbs. By allowing deforested areas to remain unattended for a long time, the regrowth of forests can happen spontaneously and without the help of humans.

Old stands must be left alone or have had afforestation rehabilitation and been given time to mature to the point of generating seeds in order for natural regeneration to occur. The majority of Central and Eastern European nations as well as Scandinavian nations are like this.

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Explanation:

Yes, they do they let consumers know about possible allergens and nutritional value.They can also assist those keeping to a diet.