match it in the correct order
gottesman rf, coresh j, catellier dj, et al. blood pressure and white-matter disease progression in a biethnic cohort: atherosclerosis risk in communities (aric) study. stroke 2010;41:3-8.
Background and purpose: Blood stress (BP) is a predictor of concurrent and subsequently measured white-matter hyperintensity (WMH), but longitudinal research of WMH changes and facts in black members is lacking. We hypothesized that WMH development would be (1) strongly associated with BP in blacks and whites and (2) predicted greater strongly with the aid of previously (midlife) or cumulative BP measurements than through measures at older ages.
Methods: Participants have been 983 folks (49% black) from the Atherosclerosis Risk in Communities (ARIC) Study who underwent cerebral magnetic resonance imaging in 1993-1995 and 2004-2006. Associations between BP (measured at each of 5 visits, in addition to a time-averaged cumulative BP) and progression of WMHs have been analyzed and compared.
Results: Cumulative systolic BP (SBP) used to be the strongest BP predictor of WMH development in adjusted models. Higher cumulative SBP (by 20 mm Hg) was related to the greater progression of WMHs and used to be similar in blacks (2.5 cm(3), P<0.0001) and whites (2.6 cm(3), P<0.0001). Higher cumulative SBP(per 20 mm Hg) was additionally associated with being in the pinnacle quintile of WMH development (adjusted odds ratio=2.0; 95% CI, 1.6 to 2.6). Earlier SBP measurements were more desirable predictors of WMH development than have been later SBP measurements, however in blacks only.
Conclusions: In this population-based cohort, cumulative SBP was once a better predictor of WMH progression than SBP from character visits, in both blacks and whites. Earlier BPs had been superior predictors than BPs measured at later time factors in blacks only.
Blood stress is measured the use of two numbers: The first number, known as systolic blood pressure (SBP), measures the pressure in your arteries when your heart beats. The 2nd number, known as diastolic blood pressure, measures the strain in your arteries when your coronary heart rests between beats.
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list and describe, in order, the tissue changes resulting from continued reduction of blood circulating to the foot until amputation is necessary
Until amputation, there is pain and redness, a change in color and the tissue begins to harden.
What is amputation?Loss or removal of a body part, such as a finger, toe, hand, foot, arm, or leg, is known as amputation. Your capacity to travel, work, communicate with others, and maintain your independence may all be impacted by this potentially life-changing experience.Upper and lower amputations are often the initial amputation kinds that doctors categorize. In upper amputations, the fingers, wrist, or arm are affected. Toes, ankles, or legs are involved in lower amputations.The surgeon separates healthy tissue from diseased tissue. This comprises nerves, blood vessels, bone, muscle, and skin. The injured portion of the limb is then removed by the surgeon. Shortening the remaining nerves allows them to pull back into the healthy tissue.Learn more about the Amputation with the help of the given link:
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when a prairie dog spots a predator, it responds by giving an alarm call, but only when close relatives are near. this is an example of .
when a prairie dog spots a predator, it responds by giving an alarm call, but only when close relatives are near. this is an example of vocalization.
What do you mean by predator ?The interaction between prey and a predator, where the energy flow occur called as predation and the organism feed on other organism called as predator and the food means the other organism is called as prey.
Predators can be carnivores and omnivores like Lions, tigers, sharks, and snakes, all are predators, it can fall prey to other large animals E.g. a snake is a predator to a mouse, but prey to a hawk.
Carnivorous predators directly kill and eat their prey like large animals such as the lion and tiger, they have their own mode of feeding.
Herbivore are plant eating animals like cows, buffaloes, goats, sheep, and deer; parasites are also under the category of predators which is a host dependent and live, get nutrients from host's body for survival and reproduction.
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A scientist is studying three different layers of sedimentary rock to learn how a particular mammal species has changed over time. In the rock layer that is closest to the Earth's surface, fossilized individuals of this species have hooves on both their front feet and their back feet. In the layer below, fossilized individuals have three padded toes on both their front feet and their back feet. In the bottom layer, fossilized individuals have four padded toes on their front feet and three padded toes on their back feet.
Based on this information, individuals of this species today most likely have
A. hooves on both their front feet and their back feet.
B. four padded toes on their front feet and three padded toes on their back feet.
C. four padded toes on both their front feet and their back feet.
D. three padded toes on both their front feet and their back feet.
Answer:
A.
Explanation:
hooves are most likely as the higher layers are the most recent. althoguh the animals used to have some configuration of 3 or 4 toes on their back or front feet, the most recent data tells us that they evolved to have hooves
Based on this information, individuals of this species today most likely have hooves on both their front feet and their back feet. The correct answer is option A.
What is the study like these called as ?
It is called as paleontology. The study of such fossils and the rocks in order to predict the future like these is done by paleontologist.
With the studies and the observation that are given in the situation where the organisms have developed a situation where the presence of hooves is present on both front and back hooves.
This usually takes place in the horses where the toes are present on both front and back. In order to study the pattern as when the organism has changed in which way then in this case, the best proof is the present scenario.
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Two separate polypeptide chains are most commonly covalently linked to each other through.
Two separate polypeptide chains are most commonly covalently linked to each other through disulfide bonds.
A peptide is two or more amino acids that are held together with the help of peptide bonds
A protein chain has two ends: one is the amino terminus (positively charged) and the other one is the carboxy terminus (negatively charged).
Disulfide bonds which are mostly found between the sulfur-containing side chains of cysteines contribute to the formation of the tertiary structure of proteins.
These bonds act like safety pins as they keep the different polypeptide chains held together firmly and give a shape to the protein folding.
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The division of human cells consists of a series of events, collectively called ________, or nuclear division, and ________, or division of the cytoplasm.
glucose binds to glycogen phosphorylase and competitively inhibits the enzyme. what is the physiological advantage of this?
This mechanism allows the glycogen phosphorylase activity to be the regulated by the concentration of the glucose so that the glycogen is not be broken down when the glucose is already plentiful.
The enzyme that glycogen phosphorylase is fundamentally important in the glucose metabolism. It is catalyzes the release of the glucose monomers from the glycogen and polymer stored in the liver (glycogenolysis). Glycogen is to be broken down by the GP to produce the glucose-1-phosphate (G-1-P) in the reaction that does not have require ATP Glycogen phosphorylases (GP) catalyzes the degradation of reducing the end of glycogen into the glucose-1-phosphate. It employs the cofactor called as pyridoxal-5' –phosphate, that is be located in the active site and the bound to a K681 residue with the Schiff base linkage.
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chemogenetic manipulations of ventral tegmental area dopamine neurons reveal multifaceted roles in cocaine abuse
Dopamine (DA) neurons in the ventral tegmental area (VTA) have a variety of functions in motivation and cognition, although it is unclear exactly how these functions link to behaviors associated with addiction.
In this study, we investigated the roles of inhibitory and excitatory G-protein signaling in the processes of cocaine reinforcement, demand, and relapse in male rats by focusing on VTA DA neurons for bidirectional chemogenetic regulation. By employing functionally amazing projections to forebrain limbic regions, designer receptor stimulation of Gq signaling, but no longer Gs signaling, in DA neurons leads to cocaine searching that is more appropriate.
Contrarily, activating inhibitory Gi/o signaling in DA neurons reduced stress-potentiated reinstatement, altered cocaine-seeking and -taking behavioral strategies, and dampened the reinforcing and priming effects of cocaine. Although ventral tegmental area (VTA) dopamine neuron activity is fundamentally regulated by G-protein-coupled receptors, it is unclear how this metabotropic signaling affects the intricate roles of dopamine in reward and dependence. Here, we use designer receptors exclusively activated by dressmaker drugs (DREADDs) to modulate dopamine neuron G-protein signaling in a bidirectional manner during a range of cocaine-seeking behaviors, revealing complex, pathway-specific roles in cocaine reward, effortful seeking, and relapse-like behaviors.
Dopamine neurons were triggered by both Gq and Gs activation, however, only Gq stimulation is much more appealing to cocaine seekers. Some types of cocaine seeking were reduced, but not all of them, by Gi/o inhibitory signaling. Results show that VTA dopamine neurons regulate a number of amazing aspects of cocaine addiction- and relapse-related behaviors and they suggest potentially effective novel strategies for doing so.
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Name the rod-shaped organelles that have a double-membrane wall and that oxidize foodstuffs to make atp.
The double-membrane system that surrounds mitochondria is made up of inner and outer mitochondrial membranes that are separated by an intermembrane space.
Cristae, or folds, are formed by the inner membrane and extend into the matrix, or interior, of the organelle.The elements of the electron transport chain are found in the mitochondrion's inner membrane. The electron transport chain's components undergo oxidation and reduction reactions, which provide a proton gradient that ATP synthase uses to phosphorylate ADP and produce ATP.More than 90% of the energy in your body's cells is produced by mitochondria, which act as batteries in the cells.In high-energy-demanding organs including your heart, liver, muscles, and brain, mitochondria play a critical role.Mitochondria make about 25% of liver cells and 40% of heart muscle cells, respectively.Learn more about mitochondria here:
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in order for an organism to survive, what must it do? reproduce reproduce find food and water find food and water regenerate regenerate select a habitat select a habitat
Select a Habitat
All living things require the following five things to survive: sunshine, water, air, habitat, and food. These fundamental requirements support our cells' healthy operation in several ways.
An energy source and the capacity for reproduction are two elements that all living creatures require to exist. Water presumably as well, but if we ever find a creature that doesn't require water, the other two should still be true.
A sandwich, the sun, or minerals are all examples of energy sources. To survive, organisms require fuel. Even if they may only require a small quantity over a long time, nothing can exist without any resources
. Every living thing must reproduce. Nothing we are aware of is immoral.
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predict what you think will happen to the ions in each compartment as soon as we allow potassium to move.
C. One ion moves down its gradients will happen to the ions in each compartment as soon as to allow potassium to move.
Ion- An atom or collection of atoms with a positive or negative electric charge as a result of either gaining or losing one or more electrons. Ions are charged subatomic particles (like a free electron). For Example, [tex]K^{+2} , Na^{+}[/tex]
Ionic Gradient- The term "concentration gradient" refers to the differential in an ion's concentration along its two plasma membrane sides. Ions passively go from a medium with a high concentration to one that has a low concentration via open channels.
The given question is incomplete, find below the complete question,
Q. Predict what you think will happen to the ions in each compartment as soon as we allow potassium to move.
a. No net movement of ions.
b. Two ions move down their gradients.
c. One ion moves down its gradients.
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describe at least three structures made of dense regular connective tissue and three made of dense irregular connective tissue. quizlet
Tendons, ligaments are made up of dense connective tissue with collagen fibers that are more densely packed. The specialized connective tissues of adipose tissue, bone, blood, cartilage and lymph are only a few examples.
The lymph nodes, some forms of fascia, and the submucosa of the intestinal tract are all made of dense, erratic connective tissue. Other examples are the tunica albuginea of the testis and the periosteum and perichondrium of bones. In bodily areas that require support to fend against forces coming from various directions, dense, uneven connective tissue is concentrated in high amounts.
Tissue that provides structure, support, and protection to other human tissues and organs. Connective tissue also stores fat, transports nutrients and other things between tissues and organs, and repairs damaged tissue. A gel-like substance, fibers, and cells make up connective tissue.
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if a parent with the genotype aa bb mates with a parent who is aa bb, what is the probability of an aa bb offspring?
When a parent with the genotype aabb mates with a parent who is aabb, the probability of an aabb offspring will be 100 % because it is a homozygous recessive condition.
The genotype refers to the genetic constitution of an organism. It provides knowledge about the alleles of the gene involved. It also tells if the trait is homozygous or heterozygous, dominant or recessive.
Homozygous recessive refers to the genotype where both the alleles of a gene are of similar type. Being recessive means that these alleles are only expressed when they are together in a homozygous state. With a dominant allele, the effect of recessive allele is completely masked.
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A root cell may continue to absorb minerals even though the concentration of the minerals is greater inside the cell than in the soil. This absorption is accomplished mainly by —.
Answer:
active transport
Explanation:
works from a low concentration to a high concentration - against a concentration gradient
define the term species
in vitro activity of cp65,207, a new penem antimicrobial agent, in comparison with those of other agents
The correct answer is because it had the highest affinity for penicillin-binding proteins 2, 1A, 1B, and 3 in cell-free Escherichia coli W-7 preparations.
CP-65,207 is a new parenteral penem antibiotic with a broad spectrum that includes gram-positive, gram-negative, and anaerobic microorganisms, with MICs less than or equal to 1 microgram/ml for 90% (MIC90s) of the majority of 1,101 clinical pathogens tested. The compound was 10- to 100-fold more active against gram-positive bacteria and anaerobes than cefoxitin and broad-spectrum cephalosporins. For staphylococci, group A streptococci, and Enterococcus faecalis, CP-65,207 was less effective than imipenem. CP-65,207 was 100-fold more active than cefoxitin, 5- to 10-fold more active than broad-spectrum cephalosporins, and 2-fold more active than imipenem against members of the family than imipenem against members of the antimicrobial family.
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according to the smcre model, presenters have the most control over the source variable because they can take control of their appearance. group of answer choices true.
The given statement is False.
What is Gene?The term "gene" has a variety of meanings in biology. The molecular is a sequence of DNA nucleotides that is transcribed to form a functional RNA, whereas the Mendelian gene is the fundamental unit of inheritance. Protein-coding genes and non - protein coding genes are the two categories of molecular genes.
DNA is initially transcribed into RNA during gene expression. The RNA may execute a specific function directly or may serve as an intermediary template for a protein. The basis for the acquisition of phenotypic traits is the transfer of genetics to an organism's progeny. These genes that make up several genotypes, which are DNA sequences.
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is part of the keratin found in your hair and skin. it also helps with the formation of collagen (the most abundant protein in the human body), maintains the body's acid-base balance, and assists in cellular respiration (the process in which cells produce the energy they need to survive).
Sulfur is part of the keratin found in your hair and skin. it also helps with the formation of collagen.
Keratin and collagen belong to the class of fibrous proteins and are essential proteins for the development and growth of strong healthy hair.
Keratin exists in the body as alpha and beta cells and is composed of keratinocyte cells.
Collagen is present in connective tissues and is an extremely vital component that maintains the structure of tresses.
It also contributes to the production of keratin to maintain and promote the health of hair follicles.
Moreover, these two components are also found in the nails, skin, claws, hoofs, and hair.
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a species of bat nearly went extinct due to the destruction of its forest habitat. however, conservationists preserved a small remnant population of the species in a large forested reserve. the population grew and it appeared that the species would rebound when a disease suddenly wiped out the entire population. what is the likely primary reason for why this occurred?
The possible reason for this phenomenon is the low genetic diversity of the species of bat.
What is Reserve Forest?A nature reserve is a safe area that is managed for conservation purposes and to offer unique chances for research or study. It is important for flora, animals, or characteristics of geologic or other specific interests. In some nations, government agencies may identify them, as well as private landowners like charities and research facilities.
Depending on the degree of coverage provided by local regulations, nature reserves are categorized into various IUCN categories. It is typically subject to stricter protection than a natural park. Other terms, such as ecologically security area or private conservation area, may be used by different governments in their laws and official names for the reserves.
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question 5(multiple choice worth 4 points) (04.02 mc) which description properly describes the plant structures involved in photosynthesis? stomata take in water, sunlight, and carbon dioxide and release oxygen. phloem transports water, stomata take in carbon dioxide, and chlorophyll absorbs sunlight. phloem transports glucose to the plant, and stomata release oxygen. xylem takes in water, sunlight, and carbon dioxide and releases oxygen.
The right response is that "stomata absorb carbon dioxide, chlorophyll absorbs sunlight, and xylem transfers water."
How does photosynthesis work? Describe the make-up of plants.Plants manufacture oxygen and sugar-based energy through a process known as photosynthesis, which uses sunlight, water, and carbon dioxide. Water (H₂O) and carbon dioxide (CO₂) are ingested by plants during photosynthesis from the soil and atmosphere. In contrast to the carbon dioxide, which is reduced within the plant cell and obtains electrons, water is oxidized within the cell of the plant. Water is converted into oxygen and carbon dioxide into glucose as a result. Once the oxygen has been returned to the atmosphere, the plant stores energy inside the molecules of glucose.
The xylem and phloem are two vascular components in plants that transport water and nutrients, respectively. The plant's gas exchange is carried out by the stomata (plural: stoma) (which take in carbon dioxide and release oxygen). The green color of the leaves is primarily due to chlorophyll, which is an organelle found in plant cells that is involved in photosynthesis.
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What will be the effect on protein function if each polypeptide adopted only a single, inflexible shape based on its primary structure.
If each polypeptide adopted only a single, inflexible shape based on its primary structure, the proteins' ability to regulate activity will be impaired.
In such a case, a protein will either be completely active or inactive, based on how they are folded.
Proteins are complex molecules composed of long chains of amino acids.
While protein folding refers to how these linear chains of amino acids are folded to render a biologically active protein.
If there is any abnormality in the folding, there will be no interaction with corresponding molecular partners and the protein will remain inactive which can harm various functions of the body.
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Give one example of something from
each of the 4 spheres that you might find
in a forest near Plainfield, Illinois.
Four elements that you might find near Plainfield, Illinois that are related to the four spheres are oxygen (atmosphere), the lake (hydrosphere), white oak tree (biosphere), and hills (geosphere).
What are the spheres of Earth?The main spheres of our planet Earth are:
Atmosphere: This refers to the layer of gas that surrounds the surface.Biosphere: All living beings such as animals, plants, fungi, bacteria, etc.Geosphere: Inanimated objects such as rocks or mountains.Hydrosphere: Elements including water such as rivers or lakes.Another sphere some authors include is the cryosphere, which included glaciers, and icebergs, among others.
What elements can be found near Plainfield, Illinois?Atmosphere: Oxygen, carbon dioxide, nitrogen, and other regular gases found in the area.Biosphere: White oak, which is a common tree species in this state, and this region.Geosphere: Hills found in the nearby area.Hydrosphere: The Plainfield lake, which can be sound in this area.
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which of the statements offers the most compelling evidence for the connection of all life on earth? group of answer choices the frequency with which convergent evolution takes place the fact that dna is universal to all life forms very similar morphologies among groups of organisms evolution cannot be observed directly, so there is no compelling evidence for this. the fossil record
The most compelling evidence for the connection of all life on earth will be "the fossil record".
The fossil record is the collection of all fossils over time that have been chronologically ordered. The existence of ancient life is demonstrated by the fossil record, which also shows how some living creatures changed over very long epochs (evolved), enabling them to endure shifting conditions.
The most compelling evidence for the connection of all life on earth
Anatomy species may share similar physical features because the feature was present in a common ancestor or the homologous structures).Molecular biology. DNA and the genetic code reflect the shared ancestry of life. DNA comparisons can show how related species are.Biogeography. The global distribution of organisms and the unique features of island species reflect evolution and geological change.Fossils documentary that how existence of now-extinct past species are related to present-day species.To know more about life on earth here
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What does solid benzene do in liquid benzene?
Answer:
Sink
Explanation:
So here for the explanation when water freezes, it forms crystalline, solid with a lower density. Then it had as a liquid because off this difference in the density, eyes floats on water. Most liquids, such as bending, have a higher density as our solid causing solid benzene to sink in liquid benzene bending is more normal in this behavior.
What are two major plant adaptations that were most important in allowing plants to become independent of aquatic habitats?.
Two major adaptations that were most important in allowing plants to become independent of aquatic habitats are the vascular system and seeds.
In order for plants to survive on land, they need a proper vascular system for the transport of food and water. Also, if not water, then another source should be present for plants for fertilization and protecting their embryos.
The presence of the vascular system is an adaptation that allowed plants to survive in land habitats. The xylem vascular system is responsible for transporting water from the soil to all the other parts of the plant. The phloem vascular bundle is responsible for the transportation of food from the leaves to all other parts of the plant.
The development of seeds in plants allowed a secure method for dispersal as seeds protect the embryos of plants and are also transported through means such as animals, winds etc.
Although a part of your question is missing, you might be referring to this question:
What are two major plant adaptations that were most important in allowing plants to become independent of aquatic habitats?
a. photosynthesis and symbiotic relationship with fungi
b. vascular system and seeds
c. bilateral symmetry and becoming multicellular organisms
d. spore production and becoming single-celled organisms
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thomopoulos s, marquez jp, weinberger b, et al. 2006. collagen fiber orientation at the tendon to bone insertion and its influence on stress concentrations. j biomech 39: 1842–1851.
The extracellular matrix of connective tissues contains fibers called collagen fibers that are elongated and comprised of collagen glycoproteins.
How does collagen fibre influence stress concentration?The mechanical function of the tendon to bone insertion is to transfer loads from a relatively flexible tendon to a relatively inflexible bone. Given the high failure rates of existing surgical techniques for tendon reattachment, the specifics of the process of weight transfer are crucial. The mean angles of the local distributions varied slightly from the tendon axis, and the angular deviation of the fibers was quite constant throughout the insertion. These distributions were utilized to determine material characteristics for an idealized two-dimensional mechanical model of an insertion, which allowed us to investigate how these observed property distributions could affect load transfer.Learn more about the collagen with the help of the given link:
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True / False: DNA does not have the information needed to copy itself.
Answer:
true
Explanation:
Before a cell divides, its DNA is replicated (duplicated.)
Answer:TRUE
Explanation:
blood the american society of hematology inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts
The American society of hematology suggests that osteoblasts can act as a therapeutic target for inhibition of leukemia cell engraftment and disease progression in mice.
Theoretically, the hematological cancers' genesis or development depend on the presence of a favorable microenvironment in the bone marrow niche. It was suggested that leukemic blasts are influenced by osteoblasts, niche elements vital to hematopoietic stem cell (HSC) activity. The study showed that individuals with acute myeloid leukemia and myelodysplasia experience a 55% drop in osteoblast counts. Additionally, in mice models of acute leukemia, genetic osteoblast depletion increased the number of circulating blasts and tumor engraftment in the marrow and spleen, which resulted in a greater tumor burden and shorter survival. Hematopoietic lineage/progression may have been changed since myelopoiesis increased, it was accompanied by a decline in B lymphopoiesis, and was impaired by erythropoiesis.
Osteoblast loss was prevented in mice with acute myeloid or lymphoblastic leukemia treated with a pharmaceutical inhibitor of the production of duodenal serotonin, a hormone that reduces the number of osteoblasts. Maintaining the osteoblast pool reduced tumor burden, extended life, and restored normal marrow function. Because inhibition of serotonin receptors alone in leukemic blasts did not impact leukemia development, leukemia prevention was attributed to maintaining osteoblast numbers. These findings imply that osteoblasts are essential for leukemia growth in the bone marrow and may serve as a therapeutic target to make the niche hostile to leukemia blasts.
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Viruses contain genetic material which carries the instructions for the construction of new virus particles. This genetic material is primarily composed of-
A. Phospholipids
B. Polysaccharides
C. Nucleic acids
D. Polypeptides
The genetic material of viruses is primarily composed of: (C) Nucleic acids.
Viruses contain a protein coat (capsid) which protects the genetic material, which could be either RNA (ribonucleic acid) or DNA (deoxyribonucleic acid), both of which are nucleic acids. A virus cannot contain both DNA and RNA at the same time.
A virus is a nucleoprotein and the genetic material (RNA or DNA) is infectious which contains the information for the genesis of new virus particles. Generally, plant-infecting viruses contain single stranded RNA and viruses which infect animals may contain either single or double stranded RNA or double stranded DNA.
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